Ecor1 Capital, LLC

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 44Value: $1.6BLatest: 2025Q1

EcoR1 Capital, LLC is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 44 holdings worth $1.6 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "AKRO",
  "ORIC",
  "JAZZ",
  "MDGL",
  "APLS",
  "GLPG",
  "DNA",
  "PRME",
  "TCRX",
  "ANAB",
  "BCYC",
  "TNGX",
  "RLAY",
  "TECX",
  "REPL",
  "KROS",
  "PRTA",
  "NGNE",
  "ALGS",
  "JANX",
  "ATRA",
  null,
  "WHWK",
  null,
  null,
  "ZYME",
  "UPB",
  "RNA",
  "MBX",
  "SLDB",
  "QURE",
  "ADAP",
  "SRPT",
  "IMNM",
  "KLRS",
  "KURA",
  "ETON",
  "VERV",
  "VYGR",
  "XNCR",
  "BEAM",
  "CRNX",
  "CRSP",
  "DAWN"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 44
Total Value: 1618567932
Accession Number: 0000935836-25-000338
Form Type: 13F-HR
CIK: ecor1-capital
Manager Name: Ecor1-Capital

Data Enrichment

93% identified

41 identified3 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

44 positions • $1.6B total value

SEC FilingSEC DataHachi Filing

Manager:

Search and click to pin securities to the top

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Apellis Pharmaceuticals, Inc.

APLS|03753U106

Shares:11.9M

Value:$260.2M

% of Portfolio:16.1% ($260.2M/$1.6B)

Jazz Pharmaceuticals plc

JAZZ|G50871105

Shares:1.7M

Value:$211.9M

% of Portfolio:13.1% ($211.9M/$1.6B)

Zymeworks Inc.

ZYME|98985Y108

Shares:17.3M

Value:$205.6M

% of Portfolio:12.7% ($205.6M/$1.6B)

ANAPTYSBIO, INC

ANAB|032724106

Shares:7.9M

Value:$146.5M

% of Portfolio:9.1% ($146.5M/$1.6B)

Crinetics Pharmaceuticals, Inc.

CRNX|22663K107

Shares:4.3M

Value:$143.8M

% of Portfolio:8.9% ($143.8M/$1.6B)

PROTHENA CORP PUBLIC LTD CO

PRTA|G72800108

Shares:11.6M

Value:$143.4M

% of Portfolio:8.9% ($143.4M/$1.6B)

Sarepta Therapeutics, Inc.

SRPT|803607100

Shares:1.3M

Value:$82.5M

% of Portfolio:5.1% ($82.5M/$1.6B)

Xencor Inc

XNCR|98401F105

Shares:6.1M

Value:$65.4M

% of Portfolio:4.0% ($65.4M/$1.6B)

CRISPR Therapeutics AG

CRSP|H17182108

Shares:1.4M

Value:$47.3M

% of Portfolio:2.9% ($47.3M/$1.6B)

Janux Therapeutics, Inc.

JANX|47103J105

Shares:1.5M

Value:$39.7M

% of Portfolio:2.5% ($39.7M/$1.6B)

Immunome Inc.

IMNM|45257U108

Shares:4.1M

Value:$27.5M

% of Portfolio:1.7% ($27.5M/$1.6B)

MADRIGAL PHARMACEUTICALS, INC.

MDGL|558868105

Shares:75.0K

Value:$24.8M

% of Portfolio:1.5% ($24.8M/$1.6B)

Oric Pharmaceuticals, Inc.

ORIC|68622P109

Shares:3.4M

Value:$19.1M

% of Portfolio:1.2% ($19.1M/$1.6B)

Akero Therapeutics, Inc.

AKRO|00973Y108

Shares:440.0K

Value:$17.8M

% of Portfolio:1.1% ($17.8M/$1.6B)

Kura Oncology, Inc.

KURA|50127T109

Shares:2.6M

Value:$17.4M

% of Portfolio:1.1% ($17.4M/$1.6B)

Tectonic Therapeutic, Inc.

TECX|878972108

Shares:935.1K

Value:$16.6M

% of Portfolio:1.0% ($16.6M/$1.6B)

Avidity Biosciences, Inc.

RNA|05370A108

Shares:557.6K

Value:$16.5M

% of Portfolio:1.0% ($16.5M/$1.6B)

Neurogene Inc.

NGNE|64135M105

Shares:1.3M

Value:$14.9M

% of Portfolio:0.9% ($14.9M/$1.6B)

Tango Therapeutics, Inc.

TNGX|87583X109

Shares:10.6M

Value:$14.6M

% of Portfolio:0.9% ($14.6M/$1.6B)

Voyager Therapeutics, Inc.

VYGR|92915B106

Shares:3.9M

Value:$13.2M

% of Portfolio:0.8% ($13.2M/$1.6B)

Instrument	Shares		Other Manager	Value	% of Portfolio
Apellis Pharmaceuticals, Inc.(APLScusip03753U106)	11.9M	QoQ +0.04% (-5.0K) YoY +4.74% (-538.4K)	All Managers (Combined)	$260.2M	16.1% ($260.2M/$1.6B)	QoQ -31.43% (-$119.3M) YoY -61.02% (-$407.4M)
Jazz Pharmaceuticals plc(JAZZcusipG50871105)	1.7M	QoQ 0.00% (+0) YoY +68.29% (+692.5K)	All Managers (Combined)	$211.9M	13.1% ($211.9M/$1.6B)	QoQ +0.81% (+$1.7M) YoY +73.51% (+$89.8M)
Zymeworks Inc.(ZYMEcusip98985Y108)	17.3M	QoQ +14.84% (-2.2M) YoY +28.44% (+3.8M)	All Managers (Combined)	$205.6M	12.7% ($205.6M/$1.6B)	QoQ -6.56% (-$14.4M) YoY +45.41% (+$64.2M)
ANAPTYSBIO, INC(ANABcusip032724106)	7.9M	QoQ +0.08% (+6.6K) YoY +4.77% (-359.1K)	All Managers (Combined)	$146.5M	9.1% ($146.5M/$1.6B)	QoQ +40.52% (+$42.2M) YoY -13.51% (-$22.9M)
Crinetics Pharmaceuticals, Inc.(CRNXcusip22663K107)	4.3M	QoQ 0.00% (-0) YoY +3.19% (-132.7K)	All Managers (Combined)	$143.8M	8.9% ($143.8M/$1.6B)	QoQ -34.40% (-$75.4M) YoY -26.05% (-$50.7M)
PROTHENA CORP PUBLIC LTD CO(PRTAcusipG72800108)	11.6M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$143.4M	8.9% ($143.4M/$1.6B)	QoQ -10.64% (-$17.1M) YoY -50.04% (-$143.6M)
Sarepta Therapeutics, Inc.(SRPTcusip803607100)	1.3M	QoQ +67.84% (-522.4K) YoY -32.68% (-627.4K)	All Managers (Combined)	$82.5M	5.1% ($82.5M/$1.6B)	QoQ -11.90% (-$11.1M) YoY -66.81% (-$166.1M)
Xencor Inc(XNCRcusip98401F105)	6.1M	QoQ 0.00% (-0) YoY +15.27% (-814.4K)	All Managers (Combined)	$65.4M	4.0% ($65.4M/$1.6B)	QoQ -53.69% (-$75.8M) YoY -44.57% (-$52.6M)
CRISPR Therapeutics AG(CRSPcusipH17182108)	1.4M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$47.3M	2.9% ($47.3M/$1.6B)	QoQ -13.54% (-$7.4M) YoY -50.07% (-$47.4M)
Janux Therapeutics, Inc.(JANXcusip47103J105)	1.5M	QoQ 0.00% (-0) YoY NEW(+1.5M)	All Managers (Combined)	$39.7M	2.5% ($39.7M/$1.6B)	QoQ -49.57% (-$39.0M) YoY NEW(+$39.7M)
Immunome Inc.(IMNMcusip45257U108)	4.1M	QoQ +5.15% (-200.0K) YoY +5.15% (-200.0K)	All Managers (Combined)	$27.5M	1.7% ($27.5M/$1.6B)	QoQ -33.36% (-$13.7M) YoY -71.32% (-$68.3M)
MADRIGAL PHARMACEUTICALS, INC.(MDGLcusip558868105)	75.0K	QoQ 0.00% (+0) YoY 0.00% (+0)	All Managers (Combined)	$24.8M	1.5% ($24.8M/$1.6B)	QoQ +7.34% (+$1.7M) YoY +24.03% (+$4.8M)
Oric Pharmaceuticals, Inc.(ORICcusip68622P109)	3.4M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$19.1M	1.2% ($19.1M/$1.6B)	QoQ -30.85% (-$8.5M) YoY -59.41% (-$27.9M)
Akero Therapeutics, Inc.(AKROcusip00973Y108)	440.0K	QoQ NEW(+440.0K) YoY NEW(+440.0K)	All Managers (Combined)	$17.8M	1.1% ($17.8M/$1.6B)	QoQ NEW(+$17.8M) YoY NEW(+$17.8M)
Kura Oncology, Inc.(KURAcusip50127T109)	2.6M	QoQ -25.77% (-917.0K) YoY +277.18% (+1.9M)	All Managers (Combined)	$17.4M	1.1% ($17.4M/$1.6B)	QoQ -43.75% (-$13.6M) YoY +16.70% (+$2.5M)
Tectonic Therapeutic, Inc.(TECXcusip878972108)	935.1K	QoQ +10.12% (-86.0K) YoY NEW(+935.1K)	All Managers (Combined)	$16.6M	1.0% ($16.6M/$1.6B)	QoQ -57.75% (-$22.6M) YoY NEW(+$16.6M)
Avidity Biosciences, Inc.(RNAcusip05370A108)	557.6K	QoQ 0.00% (+0) YoY -26.39% (-200.0K)	All Managers (Combined)	$16.5M	1.0% ($16.5M/$1.6B)	QoQ +1.51% (+$245.3K) YoY -14.86% (-$2.9M)
Neurogene Inc.(NGNEcusip64135M105)	1.3M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$14.9M	0.9% ($14.9M/$1.6B)	QoQ -48.77% (-$14.2M) YoY -76.99% (-$49.8M)
Tango Therapeutics, Inc.(TNGXcusip87583X109)	10.6M	QoQ 0.00% (-0) YoY -20.25% (-2.7M)	All Managers (Combined)	$14.6M	0.9% ($14.6M/$1.6B)	QoQ -55.66% (-$18.3M) YoY -86.24% (-$91.3M)
Voyager Therapeutics, Inc.(VYGRcusip92915B106)	3.9M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$13.2M	0.8% ($13.2M/$1.6B)	QoQ -40.38% (-$9.0M) YoY -63.69% (-$23.2M)