Frazier Life Sciences Management, L.p.

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 47Value: $2.2BLatest: 2025Q1

Frazier Life Sciences Management, L.P. is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 47 holdings worth $2.2 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "MRUS",
  "ASND",
  "TRVI",
  "ALKS",
  "KRYS",
  "NAMS",
  "ARQT",
  "RVMD",
  "ORIC",
  "ACAD",
  "MREO",
  "RCKT",
  "ALLO",
  "SLN",
  "IMTX",
  "SVRA",
  "MIRM",
  "PHAT",
  "ADVM",
  "AUTL",
  "TARS",
  "KALV",
  "MGNX",
  "LXEO",
  null,
  "PVLA",
  null,
  "RNA",
  "AGIO",
  "MBX",
  "RYTM",
  "SLNO",
  "COGT",
  "DYN",
  "ELEV",
  "ERAS",
  "IMCR",
  "DSGN",
  "HLVX",
  "VRNA",
  "ZLAB",
  "ORKA",
  "RARE",
  "PCVX",
  "BBIO",
  "CGON",
  "IRON"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 47
Total Value: 2187908599
Accession Number: 0001892134-25-000005
Form Type: 13F-HR
CIK: frazier-life-sciences-management-lp
Manager Name: Frazier-Life-Sciences-Management-Lp

Data Enrichment

96% identified

45 identified2 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

47 positions • $2.2B total value

SEC FilingSEC DataHachi Filing

Manager:

Search and click to pin securities to the top

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NewAmsterdam Pharma Co N.V.

NAMS|N62509109

Shares:16.1M

Value:$329.9M

% of Portfolio:15.1% ($329.9M/$2.2B)

Mirum Pharmaceuticals, Inc.

MIRM|604749101

Shares:6.8M

Value:$306.1M

% of Portfolio:14.0% ($306.1M/$2.2B)

Verona Pharma plc

VRNA|925050106

Shares:3.5M

Value:$219.5M

% of Portfolio:10.0% ($219.5M/$2.2B)

Arcutis Biotherapeutics, Inc.

ARQT|03969K108

Shares:8.8M

Value:$137.4M

% of Portfolio:6.3% ($137.4M/$2.2B)

BridgeBio Pharma, Inc.

BBIO|10806X102

Shares:3.8M

Value:$131.4M

% of Portfolio:6.0% ($131.4M/$2.2B)

Krystal Biotech, Inc.

KRYS|501147102

Shares:688.5K

Value:$124.1M

% of Portfolio:5.7% ($124.1M/$2.2B)

Disc Medicine, Inc.

IRON|254604101

Shares:1.8M

Value:$87.1M

% of Portfolio:4.0% ($87.1M/$2.2B)

Tarsus Pharmaceuticals, Inc.

TARS|87650L103

Shares:1.4M

Value:$71.8M

% of Portfolio:3.3% ($71.8M/$2.2B)

Trevi Therapeutics, Inc.

TRVI|89532M101

Shares:10.3M

Value:$64.5M

% of Portfolio:2.9% ($64.5M/$2.2B)

Phathom Pharmaceuticals, Inc.

PHAT|71722W107

Shares:10.1M

Value:$63.4M

% of Portfolio:2.9% ($63.4M/$2.2B)

KalVista Pharmaceuticals, Inc.

KALV|483497103

Shares:4.9M

Value:$56.4M

% of Portfolio:2.6% ($56.4M/$2.2B)

578784100

Shares:4.1M

Value:$45.5M

% of Portfolio:2.1% ($45.5M/$2.2B)

MBX Biosciences, Inc.

MBX|55287L101

Shares:6.0M

Value:$44.2M

% of Portfolio:2.0% ($44.2M/$2.2B)

RHYTHM PHARMACEUTICALS, INC.

RYTM|76243J105

Shares:678.8K

Value:$36.0M

% of Portfolio:1.6% ($36.0M/$2.2B)

SOLENO THERAPEUTICS INC

SLNO|834203309

Shares:499.2K

Value:$35.7M

% of Portfolio:1.6% ($35.7M/$2.2B)

Revolution Medicines, Inc.

RVMD|76155X100

Shares:997.5K

Value:$35.3M

% of Portfolio:1.6% ($35.3M/$2.2B)

Savara Inc

SVRA|805111101

Shares:11.5M

Value:$31.8M

% of Portfolio:1.5% ($31.8M/$2.2B)

AGIOS PHARMACEUTICALS, INC.

AGIO|00847X104

Shares:1.1M

Value:$31.3M

% of Portfolio:1.4% ($31.3M/$2.2B)

Erasca, Inc.

ERAS|29479A108

Shares:22.6M

Value:$30.9M

% of Portfolio:1.4% ($30.9M/$2.2B)

Ultragenyx Pharmaceutical Inc.

RARE|90400D108

Shares:658.7K

Value:$23.9M

% of Portfolio:1.1% ($23.9M/$2.2B)

Instrument	Shares		Other Manager	Value	% of Portfolio
NewAmsterdam Pharma Co N.V.(NAMScusipN62509109)	16.1M	QoQ +1.25% (-200.0K) YoY +31.81% (+3.9M)	All Managers (Combined)	$329.9M	15.1% ($329.9M/$2.2B)	QoQ -19.34% (-$79.1M) YoY +14.08% (+$40.7M)
Mirum Pharmaceuticals, Inc.(MIRMcusip604749101)	6.8M	QoQ +3.42% (+224.7K) YoY +4.61% (+299.7K)	All Managers (Combined)	$306.1M	14.0% ($306.1M/$2.2B)	QoQ +12.67% (+$34.4M) YoY +87.61% (+$143.0M)
Verona Pharma plc(VRNAcusip925050106)	3.5M	QoQ +2.18% (+73.9K) YoY +14.71% (+443.5K)	All Managers (Combined)	$219.5M	10.0% ($219.5M/$2.2B)	QoQ +39.69% (+$62.4M) YoY +352.64% (+$171.0M)
Arcutis Biotherapeutics, Inc.(ARQTcusip03969K108)	8.8M	QoQ 0.00% (+0) YoY 0.00% (+0)	All Managers (Combined)	$137.4M	6.3% ($137.4M/$2.2B)	QoQ +12.27% (+$15.0M) YoY +57.82% (+$50.3M)
BridgeBio Pharma, Inc.(BBIOcusip10806X102)	3.8M	QoQ 0.00% (+0) YoY +11.26% (+384.9K)	All Managers (Combined)	$131.4M	6.0% ($131.4M/$2.2B)	QoQ +25.98% (+$27.1M) YoY +24.40% (+$25.8M)
Krystal Biotech, Inc.(KRYScusip501147102)	688.5K	QoQ -12.68% (-100.0K) YoY -30.35% (-300.0K)	All Managers (Combined)	$124.1M	5.7% ($124.1M/$2.2B)	QoQ +0.49% (-$609.2K) YoY -29.42% (-$51.7M)
Disc Medicine, Inc.(IRONcusip254604101)	1.8M	QoQ 0.00% (-0) YoY +123.54% (+969.8K)	All Managers (Combined)	$87.1M	4.0% ($87.1M/$2.2B)	QoQ -21.70% (-$24.1M) YoY +78.23% (+$38.2M)
Tarsus Pharmaceuticals, Inc.(TARScusip87650L103)	1.4M	QoQ -11.96% (-190.0K) YoY -21.81% (-390.0K)	All Managers (Combined)	$71.8M	3.3% ($71.8M/$2.2B)	QoQ -18.32% (-$16.1M) YoY +10.48% (-$6.8M)
Trevi Therapeutics, Inc.(TRVIcusip89532M101)	10.3M	QoQ -3.80% (-405.4K) YoY +38.99% (+2.9M)	All Managers (Combined)	$64.5M	2.9% ($64.5M/$2.2B)	QoQ +46.86% (-$20.6M) YoY +153.41% (+$39.1M)
Phathom Pharmaceuticals, Inc.(PHATcusip71722W107)	10.1M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$63.4M	2.9% ($63.4M/$2.2B)	QoQ -22.78% (-$18.7M) YoY -40.96% (-$44.0M)
KalVista Pharmaceuticals, Inc.(KALVcusip483497103)	4.9M	QoQ 0.00% (+0) YoY +32.53% (+1.2M)	All Managers (Combined)	$56.4M	2.6% ($56.4M/$2.2B)	QoQ +36.24% (+$15.0M) YoY +28.96% (+$12.7M)
(cusip578784100)✕	4.1M	QoQ NEW(+4.1M) YoY NEW(+4.1M)	All Managers (Combined)	$45.5M	2.1% ($45.5M/$2.2B)	QoQ NEW(+$45.5M) YoY NEW(+$45.5M)
MBX Biosciences, Inc.(MBXcusip55287L101)	6.0M	QoQ 0.00% (-0) YoY NEW(+6.0M)	All Managers (Combined)	$44.2M	2.0% ($44.2M/$2.2B)	QoQ -59.95% (-$66.1M) YoY NEW(+$44.2M)
RHYTHM PHARMACEUTICALS, INC.(RYTMcusip76243J105)	678.8K	QoQ -63.69% (-1.2M) YoY -69.00% (-1.5M)	All Managers (Combined)	$36.0M	1.6% ($36.0M/$2.2B)	QoQ -65.65% (-$68.7M) YoY -62.11% (-$58.9M)
SOLENO THERAPEUTICS INC(SLNOcusip834203309)	499.2K	QoQ -28.60% (-200.0K) YoY -42.99% (-376.5K)	All Managers (Combined)	$35.7M	1.6% ($35.7M/$2.2B)	QoQ +13.48% (-$4.2M) YoY -4.83% (-$1.8M)
Revolution Medicines, Inc.(RVMDcusip76155X100)	997.5K	QoQ 0.00% (-0) YoY 0.00% (+0)	All Managers (Combined)	$35.3M	1.6% ($35.3M/$2.2B)	QoQ -19.15% (-$8.4M) YoY +9.71% (+$3.1M)
Savara Inc(SVRAcusip805111101)	11.5M	QoQ +32.35% (+2.8M) YoY +186.55% (+7.5M)	All Managers (Combined)	$31.8M	1.5% ($31.8M/$2.2B)	QoQ +19.41% (+$5.2M) YoY +59.39% (+$11.8M)
AGIOS PHARMACEUTICALS, INC.(AGIOcusip00847X104)	1.1M	QoQ 0.00% (-100) YoY +104.49% (+546.7K)	All Managers (Combined)	$31.3M	1.4% ($31.3M/$2.2B)	QoQ -10.82% (-$3.8M) YoY +104.91% (+$16.0M)
Erasca, Inc.(ERAScusip29479A108)	22.6M	QoQ +16.42% (-3.2M) YoY NEW(+22.6M)	All Managers (Combined)	$30.9M	1.4% ($30.9M/$2.2B)	QoQ -36.45% (-$17.7M) YoY NEW(+$30.9M)
Ultragenyx Pharmaceutical Inc.(RAREcusip90400D108)	658.7K	QoQ 0.00% (-0) YoY NEW(+658.7K)	All Managers (Combined)	$23.9M	1.1% ($23.9M/$2.2B)	QoQ -13.92% (-$3.9M) YoY NEW(+$23.9M)