Octagon Capital Advisors LP

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 34Value: $508.2MLatest: 2025Q1

Octagon Capital Advisors LP is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 34 holdings worth $0.5 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "OCUL",
  "MRUS",
  "TRVI",
  "CNTA",
  "APLS",
  "ABVX",
  "AVBP",
  "CATX",
  "TSHA",
  "TRML",
  "NUVB",
  "MNMD",
  "PHVS",
  "SNDX",
  "NGNE",
  "SRRK",
  null,
  "KALV",
  null,
  "UNCY",
  null,
  "ATYR",
  "SPRY",
  "RGLS",
  "MLTX",
  "COGT",
  "GOSS",
  "ERAS",
  "KLRS",
  "VRNA",
  "VSTM",
  "VRDN",
  "CRBP",
  "DNTH"
]

Filing Details

13F-HR/A • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-16
Total Holdings: 34
Total Value: 508167482
Accession Number: 0001839435-25-000005
Form Type: 13F-HR/A
CIK: octagon-capital-advisors-lp
Manager Name: Octagon-Capital-Advisors-Lp

Data Enrichment

91% identified

31 identified3 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

34 positions • $508.2M total value

SEC FilingSEC DataHachi Filing

Manager:

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67080N119

Shares:27.3M

Value:$48.1M

% of Portfolio:9.5% ($48.1M/$508.2M)

Apellis Pharmaceuticals, Inc.

APLS|03753U106

Shares:2.1M

Value:$45.8M

% of Portfolio:9.0% ($45.8M/$508.2M)

Dianthus Therapeutics, Inc. /DE/

DNTH|252828108

Shares:2.3M

Value:$42.5M

% of Portfolio:8.4% ($42.5M/$508.2M)

ArriVent BioPharma, Inc.

AVBP|04272N102

Shares:2.1M

Value:$38.1M

% of Portfolio:7.5% ($38.1M/$508.2M)

Trevi Therapeutics, Inc.

TRVI|89532M101

Shares:3.3M

Value:$20.9M

% of Portfolio:4.1% ($20.9M/$508.2M)

Centessa Pharmaceuticals plc

CNTA|152309100

Shares:1.4M

Value:$20.5M

% of Portfolio:4.0% ($20.5M/$508.2M)

Gossamer Bio, Inc.

GOSS|38341P102

Shares:18.4M

Value:$20.2M

% of Portfolio:4.0% ($20.2M/$508.2M)

OCULAR THERAPEUTIX, INC

OCUL|67576A100

Shares:2.4M

Value:$17.8M

% of Portfolio:3.5% ($17.8M/$508.2M)

Mind Medicine (MindMed) Inc.

MNMD|60255C885

Shares:3.0M

Value:$17.7M

% of Portfolio:3.5% ($17.7M/$508.2M)

Cogent Biosciences, Inc.

COGT|19240Q201

Shares:2.8M

Value:$16.6M

% of Portfolio:3.3% ($16.6M/$508.2M)

KalVista Pharmaceuticals, Inc.

KALV|483497103

Shares:1.4M

Value:$15.8M

% of Portfolio:3.1% ($15.8M/$508.2M)

Taysha Gene Therapies, Inc.

TSHA|877619106

Shares:10.7M

Value:$14.9M

% of Portfolio:2.9% ($14.9M/$508.2M)

Nuvation Bio Inc.

NUVB|67080N101

Shares:7.9M

Value:$13.9M

% of Portfolio:2.7% ($13.9M/$508.2M)

Verona Pharma plc

VRNA|925050106

Shares:217.3K

Value:$13.8M

% of Portfolio:2.7% ($13.8M/$508.2M)

Tourmaline Bio, Inc.

TRML|89157D105

Shares:905.0K

Value:$13.8M

% of Portfolio:2.7% ($13.8M/$508.2M)

Merus N.V.

MRUS|N5749R100

Shares:308.0K

Value:$13.0M

% of Portfolio:2.6% ($13.0M/$508.2M)

Pharvaris N.V.

PHVS|N69605108

Shares:769.8K

Value:$12.1M

% of Portfolio:2.4% ($12.1M/$508.2M)

MoonLake Immunotherapeutics

MLTX|61559X104

Shares:296.0K

Value:$11.6M

% of Portfolio:2.3% ($11.6M/$508.2M)

Syndax Pharmaceuticals Inc

SNDX|87164F105

Shares:904.0K

Value:$11.1M

% of Portfolio:2.2% ($11.1M/$508.2M)

aTYR PHARMA INC

ATYR|002120202

Shares:3.6M

Value:$10.7M

% of Portfolio:2.1% ($10.7M/$508.2M)

Instrument	Shares		Other Manager	Value	% of Portfolio
(cusip67080N119)✕	27.3M	QoQ +8650.44% (+27.0M) YoY NEW(+27.3M)	All Managers (Combined)	$48.1M	9.5% ($48.1M/$508.2M)	QoQ +5689.76% (+$47.3M) YoY NEW(+$48.1M)
Apellis Pharmaceuticals, Inc.(APLScusip03753U106)	2.1M	QoQ -30.36% (-913.0K) YoY -25.40% (-713.0K)	All Managers (Combined)	$45.8M	9.0% ($45.8M/$508.2M)	QoQ -52.27% (-$50.2M) YoY -72.24% (-$119.2M)
Dianthus Therapeutics, Inc. /DE/(DNTHcusip252828108)	2.3M	QoQ +10.97% (-231.5K) YoY +69.60% (+961.0K)	All Managers (Combined)	$42.5M	8.4% ($42.5M/$508.2M)	QoQ -7.66% (-$3.5M) YoY +2.55% (+$1.1M)
ArriVent BioPharma, Inc.(AVBPcusip04272N102)	2.1M	QoQ 0.00% (-0) YoY +5.94% (+115.6K)	All Managers (Combined)	$38.1M	7.5% ($38.1M/$508.2M)	QoQ -30.59% (-$16.8M) YoY +9.68% (+$3.4M)
Trevi Therapeutics, Inc.(TRVIcusip89532M101)	3.3M	QoQ NEW(+3.3M) YoY NEW(+3.3M)	All Managers (Combined)	$20.9M	4.1% ($20.9M/$508.2M)	QoQ NEW(+$20.9M) YoY NEW(+$20.9M)
Centessa Pharmaceuticals plc(CNTAcusip152309100)	1.4M	QoQ -28.50% (-568.1K) YoY -30.82% (-635.1K)	All Managers (Combined)	$20.5M	4.0% ($20.5M/$508.2M)	QoQ -38.61% (-$12.9M) YoY -11.97% (-$2.8M)
Gossamer Bio, Inc.(GOSScusip38341P102)	18.4M	QoQ 0.00% (+0) YoY +99.71% (+9.2M)	All Managers (Combined)	$20.2M	4.0% ($20.2M/$508.2M)	QoQ +21.60% (+$3.6M) YoY +86.17% (+$9.3M)
OCULAR THERAPEUTIX, INC(OCULcusip67576A100)	2.4M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$17.8M	3.5% ($17.8M/$508.2M)	QoQ -14.16% (-$2.9M) YoY -19.45% (-$4.3M)
Mind Medicine (MindMed) Inc.(MNMDcusip60255C885)	3.0M	QoQ 0.00% (-0) YoY +40.17% (-865.0K)	All Managers (Combined)	$17.7M	3.5% ($17.7M/$508.2M)	QoQ -15.94% (-$3.3M) YoY -12.76% (-$2.6M)
Cogent Biosciences, Inc.(COGTcusip19240Q201)	2.8M	QoQ 0.00% (-0) YoY NEW(+2.8M)	All Managers (Combined)	$16.6M	3.3% ($16.6M/$508.2M)	QoQ -23.20% (-$5.0M) YoY NEW(+$16.6M)
KalVista Pharmaceuticals, Inc.(KALVcusip483497103)	1.4M	QoQ 0.00% (+0) YoY NEW(+1.4M)	All Managers (Combined)	$15.8M	3.1% ($15.8M/$508.2M)	QoQ +36.24% (+$4.2M) YoY NEW(+$15.8M)
Taysha Gene Therapies, Inc.(TSHAcusip877619106)	10.7M	QoQ +2.39% (-250.0K) YoY +253.13% (+7.7M)	All Managers (Combined)	$14.9M	2.9% ($14.9M/$508.2M)	QoQ -17.73% (-$3.2M) YoY +71.03% (+$6.2M)
Nuvation Bio Inc.(NUVBcusip67080N101)	7.9M	QoQ -14.15% (-1.3M) YoY +474.59% (+6.5M)	All Managers (Combined)	$13.9M	2.7% ($13.9M/$508.2M)	QoQ -43.20% (-$10.6M) YoY +177.82% (+$8.9M)
Verona Pharma plc(VRNAcusip925050106)	217.3K	QoQ -61.96% (-354.0K) YoY -90.82% (-2.2M)	All Managers (Combined)	$13.8M	2.7% ($13.8M/$508.2M)	QoQ -48.00% (-$12.7M) YoY -63.81% (-$24.3M)
Tourmaline Bio, Inc.(TRMLcusip89157D105)	905.0K	QoQ NEW(+905.0K) YoY NEW(+905.0K)	All Managers (Combined)	$13.8M	2.7% ($13.8M/$508.2M)	QoQ NEW(+$13.8M) YoY NEW(+$13.8M)
Merus N.V.(MRUScusipN5749R100)	308.0K	QoQ 0.00% (+0) YoY NEW(+308.0K)	All Managers (Combined)	$13.0M	2.6% ($13.0M/$508.2M)	QoQ +0.09% (+$12.3K) YoY NEW(+$13.0M)
Pharvaris N.V.(PHVScusipN69605108)	769.8K	QoQ -1.05% (-8.2K) YoY NEW(+769.8K)	All Managers (Combined)	$12.1M	2.4% ($12.1M/$508.2M)	QoQ -18.96% (-$2.8M) YoY NEW(+$12.1M)
MoonLake Immunotherapeutics(MLTXcusip61559X104)	296.0K	QoQ NEW(+296.0K) YoY NEW(+296.0K)	All Managers (Combined)	$11.6M	2.3% ($11.6M/$508.2M)	QoQ NEW(+$11.6M) YoY NEW(+$11.6M)
Syndax Pharmaceuticals Inc(SNDXcusip87164F105)	904.0K	QoQ 0.00% (-0) YoY NEW(+904.0K)	All Managers (Combined)	$11.1M	2.2% ($11.1M/$508.2M)	QoQ -7.07% (-$845.2K) YoY NEW(+$11.1M)
aTYR PHARMA INC(ATYRcusip002120202)	3.6M	QoQ +294.66% (+2.7M) YoY +407.42% (+2.9M)	All Managers (Combined)	$10.7M	2.1% ($10.7M/$508.2M)	QoQ +229.25% (+$7.5M) YoY +685.86% (+$9.4M)