Omega Fund Management, LLC

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 13Value: $169.5MLatest: 2025Q1

Omega Fund Management, LLC is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 13 holdings worth $0.2 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  null,
  "BCAX",
  "NUVB",
  "REPL",
  "ALMS",
  null,
  "SANA",
  "LXEO",
  null,
  "UPB",
  null,
  "IMUX",
  "IKNA"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 13
Total Value: 169462464
Accession Number: 0000950123-25-005509
Form Type: 13F-HR
CIK: omega-fund-management
Manager Name: Omega-Fund-Management

Data Enrichment

69% identified

9 identified4 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

13 positions • $169.5M total value

SEC FilingSEC DataHachi Filing

Manager:

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G52441105

Shares:1.8M

Value:$44.8M

% of Portfolio:26.4% ($44.8M/$169.5M)

Bicara Therapeutics Inc.

BCAX|055477103

Shares:2.2M

Value:$28.7M

% of Portfolio:17.0% ($28.7M/$169.5M)

08659B102

Shares:2.0M

Value:$24.3M

% of Portfolio:14.4% ($24.3M/$169.5M)

Nuvation Bio Inc.

NUVB|67080N101

Shares:13.1M

Value:$23.0M

% of Portfolio:13.6% ($23.0M/$169.5M)

Replimune Group, Inc.

REPL|76029N106

Shares:2.0M

Value:$19.3M

% of Portfolio:11.4% ($19.3M/$169.5M)

Upstream Bio, Inc.

UPB|91678A107

Shares:2.0M

Value:$12.5M

% of Portfolio:7.4% ($12.5M/$169.5M)

Lexeo Therapeutics, Inc.

LXEO|52886X107

Shares:1.2M

Value:$4.1M

% of Portfolio:2.4% ($4.1M/$169.5M)

ALUMIS INC.

ALMS|022307102

Shares:653.2K

Value:$4.0M

% of Portfolio:2.4% ($4.0M/$169.5M)

Ikena Oncology, Inc.

IKNA|45175G108

Shares:2.2M

Value:$2.9M

% of Portfolio:1.7% ($2.9M/$169.5M)

29286M105

Shares:526.4K

Value:$2.4M

% of Portfolio:1.4% ($2.4M/$169.5M)

IMMUNIC, INC.

IMUX|4525EP101

Shares:1.8M

Value:$1.9M

% of Portfolio:1.2% ($1.9M/$169.5M)

Sana Biotechnology, Inc.

SANA|799566104

Shares:843.8K

Value:$1.4M

% of Portfolio:0.8% ($1.4M/$169.5M)

29286M113

Shares:321.5K

Value:$192.9K

% of Portfolio:0.1% ($192.9K/$169.5M)

Instrument	Shares		Other Manager	Value	% of Portfolio
(cusipG52441105)✕	1.8M	QoQ NEW(+1.8M) YoY NEW(+1.8M)	All Managers (Combined)	$44.8M	26.4% ($44.8M/$169.5M)	QoQ NEW(+$44.8M) YoY NEW(+$44.8M)
Bicara Therapeutics Inc.(BCAXcusip055477103)	2.2M	QoQ NEW(+2.2M) YoY NEW(+2.2M)	All Managers (Combined)	$28.7M	17.0% ($28.7M/$169.5M)	QoQ NEW(+$28.7M) YoY NEW(+$28.7M)
(cusip08659B102)✕	2.0M	QoQ NEW(+2.0M) YoY NEW(+2.0M)	All Managers (Combined)	$24.3M	14.4% ($24.3M/$169.5M)	QoQ NEW(+$24.3M) YoY NEW(+$24.3M)
Nuvation Bio Inc.(NUVBcusip67080N101)	13.1M	QoQ NEW(+13.1M) YoY -7.10% (-1.0M)	All Managers (Combined)	$23.0M	13.6% ($23.0M/$169.5M)	QoQ NEW(+$23.0M) YoY -55.08% (-$28.2M)
Replimune Group, Inc.(REPLcusip76029N106)	2.0M	QoQ NEW(+2.0M) YoY -34.18% (-1.0M)	All Managers (Combined)	$19.3M	11.4% ($19.3M/$169.5M)	QoQ NEW(+$19.3M) YoY -21.46% (-$5.3M)
Upstream Bio, Inc.(UPBcusip91678A107)	2.0M	QoQ 0.00% (-0) YoY NEW(+2.0M)	All Managers (Combined)	$12.5M	7.4% ($12.5M/$169.5M)	QoQ -62.77% (-$21.0M) YoY NEW(+$12.5M)
Lexeo Therapeutics, Inc.(LXEOcusip52886X107)	1.2M	QoQ NEW(+1.2M) YoY -49.71% (-1.2M)	All Managers (Combined)	$4.1M	2.4% ($4.1M/$169.5M)	QoQ NEW(+$4.1M) YoY -88.87% (-$32.8M)
ALUMIS INC.(ALMScusip022307102)	653.2K	QoQ NEW(+653.2K) YoY NEW(+653.2K)	All Managers (Combined)	$4.0M	2.4% ($4.0M/$169.5M)	QoQ NEW(+$4.0M) YoY NEW(+$4.0M)
Ikena Oncology, Inc.(IKNAcusip45175G108)	2.2M	QoQ NEW(+2.2M) YoY 0.00% (-0)	All Managers (Combined)	$2.9M	1.7% ($2.9M/$169.5M)	QoQ NEW(+$2.9M) YoY -9.85% (-$314.9K)
(cusip29286M105)✕	526.4K	QoQ NEW(+526.4K) YoY -51.09% (-550.0K)	All Managers (Combined)	$2.4M	1.4% ($2.4M/$169.5M)	QoQ NEW(+$2.4M) YoY -87.07% (-$15.9M)
IMMUNIC, INC.(IMUXcusip4525EP101)	1.8M	QoQ NEW(+1.8M) YoY 0.00% (-0)	All Managers (Combined)	$1.9M	1.2% ($1.9M/$169.5M)	QoQ NEW(+$1.9M) YoY -17.42% (-$411.3K)
Sana Biotechnology, Inc.(SANAcusip799566104)	843.8K	QoQ NEW(+843.8K) YoY 0.00% (-0)	All Managers (Combined)	$1.4M	0.8% ($1.4M/$169.5M)	QoQ NEW(+$1.4M) YoY -83.20% (-$7.0M)
(cusip29286M113)✕	321.5K	QoQ NEW(+321.5K) YoY -10.91% (-39.4K)	All Managers (Combined)	$192.9K	0.1% ($192.9K/$169.5M)	QoQ NEW(+$192.9K) YoY -89.72% (-$1.7M)