Ra Capital Management, L.p.

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 85Value: $6.0BLatest: 2025Q1

RA CAPITAL MANAGEMENT, L.P. is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 85 holdings worth $6.0 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "ASND",
  "EWTX",
  "INSM",
  "NAMS",
  "CBLL",
  "ACHC",
  "RXST",
  "BCAX",
  "BCYC",
  "ATXS",
  "RCUS",
  "GPCR",
  "IMTX",
  "SCLX",
  "TVTX",
  "TSHA",
  "TRML",
  "TYRA",
  "LENZ",
  "ACET",
  "NRIX",
  "ACRV",
  "LRMR",
  "MLYS",
  "ABOS",
  "ALEC",
  "AVTX",
  "JANX",
  "ARTV",
  "BIOA",
  null,
  null,
  "GERN",
  "SRRK",
  "FULC",
  "APGE",
  "LXEO",
  null,
  "MNPR",
  "NKTX",
  "SEPN",
  "SRZN",
  "STRO",
  "GHRS",
  "TARA",
  "ACRS",
  "TXG",
  "IDYA",
  "ZURA",
  "SPRY",
  null,
  null,
  "SERA",
  "PEPG",
  "RNA",
  "MBX",
  null,
  "SLDB",
  "FDMT",
  "RYTM",
  "ACLX",
  "ETNB",
  "DYN",
  "BOLD",
  null,
  "GKOS",
  "HUMA",
  "WVE",
  null,
  "CDTX",
  "ELDN",
  "ELVN",
  "EYPT",
  "ITOS",
  "KURA",
  "URGN",
  "VOR",
  "HOWL",
  "ZLAB",
  "XNCR",
  "PCVX",
  "DAWN",
  "CTMX",
  "DNTH",
  "IRON"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 85
Total Value: 5952606666
Accession Number: 0001104659-25-049549
Form Type: 13F-HR
CIK: ra-capital-management-lp
Manager Name: Ra-Capital-Management-Lp

Data Enrichment

91% identified

77 identified8 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

85 positions • $6.0B total value

SEC FilingSEC DataHachi Filing

Manager:

Search and click to pin securities to the top

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Ascendis Pharma A/S

ASND|04351P101

Shares:10.3M

Value:$1.6B

% of Portfolio:26.9% ($1.6B/$6.0B)

Vaxcyte, Inc.

PCVX|92243G108

Shares:12.2M

Value:$460.3M

% of Portfolio:7.7% ($460.3M/$6.0B)

RHYTHM PHARMACEUTICALS, INC.

RYTM|76243J105

Shares:6.1M

Value:$322.3M

% of Portfolio:5.4% ($322.3M/$6.0B)

Janux Therapeutics, Inc.

JANX|47103J105

Shares:11.2M

Value:$302.1M

% of Portfolio:5.1% ($302.1M/$6.0B)

NewAmsterdam Pharma Co N.V.

NAMS|N62509109

Shares:10.1M

Value:$207.5M

% of Portfolio:3.5% ($207.5M/$6.0B)

Arcellx, Inc.

ACLX|03940C100

Shares:3.0M

Value:$199.2M

% of Portfolio:3.3% ($199.2M/$6.0B)

Edgewise Therapeutics, Inc.

EWTX|28036F105

Shares:8.9M

Value:$196.0M

% of Portfolio:3.3% ($196.0M/$6.0B)

Avidity Biosciences, Inc.

RNA|05370A108

Shares:6.3M

Value:$186.0M

% of Portfolio:3.1% ($186.0M/$6.0B)

Wave Life Sciences Ltd.

WVE|Y95308105

Shares:18.2M

Value:$147.1M

% of Portfolio:2.5% ($147.1M/$6.0B)

89bio, Inc.

ETNB|282559103

Shares:19.9M

Value:$144.6M

% of Portfolio:2.4% ($144.6M/$6.0B)

ARS Pharmaceuticals, Inc.

SPRY|82835W108

Shares:10.9M

Value:$136.6M

% of Portfolio:2.3% ($136.6M/$6.0B)

829401108

Shares:10.4M

Value:$109.3M

% of Portfolio:1.8% ($109.3M/$6.0B)

LENZ Therapeutics, Inc.

LENZ|52635N103

Shares:4.2M

Value:$107.4M

% of Portfolio:1.8% ($107.4M/$6.0B)

Dyne Therapeutics, Inc.

DYN|26818M108

Shares:9.7M

Value:$101.6M

% of Portfolio:1.7% ($101.6M/$6.0B)

Tyra Biosciences, Inc.

TYRA|90240B106

Shares:10.6M

Value:$98.9M

% of Portfolio:1.7% ($98.9M/$6.0B)

Mineralys Therapeutics, Inc.

MLYS|603170101

Shares:6.1M

Value:$97.6M

% of Portfolio:1.6% ($97.6M/$6.0B)

GERON CORP

GERN|374163103

Shares:60.4M

Value:$96.0M

% of Portfolio:1.6% ($96.0M/$6.0B)

RxSight, Inc.

RXST|78349D107

Shares:3.7M

Value:$94.5M

% of Portfolio:1.6% ($94.5M/$6.0B)

Bicara Therapeutics Inc.

BCAX|055477103

Shares:7.0M

Value:$90.6M

% of Portfolio:1.5% ($90.6M/$6.0B)

Disc Medicine, Inc.

IRON|254604101

Shares:1.6M

Value:$78.3M

% of Portfolio:1.3% ($78.3M/$6.0B)

Instrument	Shares		Other Manager	Value	% of Portfolio
Ascendis Pharma A/S(ASNDcusip04351P101)	10.3M	QoQ +1.66% (+168.8K) YoY NEW(+10.3M)	All Managers (Combined)	$1.6B	26.9% ($1.6B/$6.0B)	QoQ +15.10% (+$210.3M) YoY NEW(+$1602.5M)
Vaxcyte, Inc.(PCVXcusip92243G108)	12.2M	QoQ +40.27% (-3.5M) YoY NEW(+12.2M)	All Managers (Combined)	$460.3M	7.7% ($460.3M/$6.0B)	QoQ -35.29% (-$251.0M) YoY NEW(+$460.3M)
RHYTHM PHARMACEUTICALS, INC.(RYTMcusip76243J105)	6.1M	QoQ 0.00% (-0) YoY NEW(+6.1M)	All Managers (Combined)	$322.3M	5.4% ($322.3M/$6.0B)	QoQ -5.37% (-$18.3M) YoY NEW(+$322.3M)
Janux Therapeutics, Inc.(JANXcusip47103J105)	11.2M	QoQ +7.94% (-824.0K) YoY NEW(+11.2M)	All Managers (Combined)	$302.1M	5.1% ($302.1M/$6.0B)	QoQ -45.56% (-$252.9M) YoY NEW(+$302.1M)
NewAmsterdam Pharma Co N.V.(NAMScusipN62509109)	10.1M	QoQ +14.62% (-1.3M) YoY NEW(+10.1M)	All Managers (Combined)	$207.5M	3.5% ($207.5M/$6.0B)	QoQ -8.69% (-$19.8M) YoY NEW(+$207.5M)
Arcellx, Inc.(ACLXcusip03940C100)	3.0M	QoQ +8.94% (-249.2K) YoY NEW(+3.0M)	All Managers (Combined)	$199.2M	3.3% ($199.2M/$6.0B)	QoQ -6.81% (-$14.6M) YoY NEW(+$199.2M)
Edgewise Therapeutics, Inc.(EWTXcusip28036F105)	8.9M	QoQ 0.00% (-0) YoY NEW(+8.9M)	All Managers (Combined)	$196.0M	3.3% ($196.0M/$6.0B)	QoQ -17.60% (-$41.9M) YoY NEW(+$196.0M)
Avidity Biosciences, Inc.(RNAcusip05370A108)	6.3M	QoQ 0.00% (+0) YoY NEW(+6.3M)	All Managers (Combined)	$186.0M	3.1% ($186.0M/$6.0B)	QoQ +1.51% (+$2.8M) YoY NEW(+$186.0M)
Wave Life Sciences Ltd.(WVEcusipY95308105)	18.2M	QoQ 0.00% (-0) YoY NEW(+18.2M)	All Managers (Combined)	$147.1M	2.5% ($147.1M/$6.0B)	QoQ -34.68% (-$78.1M) YoY NEW(+$147.1M)
89bio, Inc.(ETNBcusip282559103)	19.9M	QoQ +40.31% (+5.7M) YoY NEW(+19.9M)	All Managers (Combined)	$144.6M	2.4% ($144.6M/$6.0B)	QoQ +30.44% (+$33.7M) YoY NEW(+$144.6M)
ARS Pharmaceuticals, Inc.(SPRYcusip82835W108)	10.9M	QoQ 0.00% (+0) YoY NEW(+10.9M)	All Managers (Combined)	$136.6M	2.3% ($136.6M/$6.0B)	QoQ +19.24% (+$22.0M) YoY NEW(+$136.6M)
(cusip829401108)✕	10.4M	QoQ NEW(+10.4M) YoY NEW(+10.4M)	All Managers (Combined)	$109.3M	1.8% ($109.3M/$6.0B)	QoQ NEW(+$109.3M) YoY NEW(+$109.3M)
LENZ Therapeutics, Inc.(LENZcusip52635N103)	4.2M	QoQ 0.00% (-0) YoY NEW(+4.2M)	All Managers (Combined)	$107.4M	1.8% ($107.4M/$6.0B)	QoQ -10.94% (-$13.2M) YoY NEW(+$107.4M)
Dyne Therapeutics, Inc.(DYNcusip26818M108)	9.7M	QoQ +52.23% (-3.3M) YoY NEW(+9.7M)	All Managers (Combined)	$101.6M	1.7% ($101.6M/$6.0B)	QoQ -32.41% (-$48.7M) YoY NEW(+$101.6M)
Tyra Biosciences, Inc.(TYRAcusip90240B106)	10.6M	QoQ 0.00% (-0) YoY NEW(+10.6M)	All Managers (Combined)	$98.9M	1.7% ($98.9M/$6.0B)	QoQ -33.09% (-$48.9M) YoY NEW(+$98.9M)
Mineralys Therapeutics, Inc.(MLYScusip603170101)	6.1M	QoQ +26.72% (+1.3M) YoY NEW(+6.1M)	All Managers (Combined)	$97.6M	1.6% ($97.6M/$6.0B)	QoQ +63.47% (+$37.9M) YoY NEW(+$97.6M)
GERON CORP(GERNcusip374163103)	60.4M	QoQ +101.20% (-30.4M) YoY NEW(+60.4M)	All Managers (Combined)	$96.0M	1.6% ($96.0M/$6.0B)	QoQ -9.63% (-$10.2M) YoY NEW(+$96.0M)
RxSight, Inc.(RXSTcusip78349D107)	3.7M	QoQ 0.00% (-0) YoY NEW(+3.7M)	All Managers (Combined)	$94.5M	1.6% ($94.5M/$6.0B)	QoQ -26.55% (-$34.2M) YoY NEW(+$94.5M)
Bicara Therapeutics Inc.(BCAXcusip055477103)	7.0M	QoQ 0.00% (-0) YoY NEW(+7.0M)	All Managers (Combined)	$90.6M	1.5% ($90.6M/$6.0B)	QoQ -25.20% (-$30.5M) YoY NEW(+$90.6M)
Disc Medicine, Inc.(IRONcusip254604101)	1.6M	QoQ NEW(+1.6M) YoY NEW(+1.6M)	All Managers (Combined)	$78.3M	1.3% ($78.3M/$6.0B)	QoQ NEW(+$78.3M) YoY NEW(+$78.3M)