Rtw Investments, LP

Investment Portfolio & 13F Holdings Analysis

About

RTW INVESTMENTS, LP is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 68 holdings worth $6.5 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 68
Total Value: 6538371722
Accession Number: 0001493215-25-000003
Form Type: 13F-HR
CIK: 0001493215
Manager Name: Rtw Investments, LP

Data Enrichment

93% identified

63 identified5 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

68 positions • $6,538,371.722K total value

68 positions

Manager:

SEC FilingSEC DataHachi Filing

Search and click to pin securities to the top

Page 1 of 4

Sort by:

MADRIGAL PHARMACEUTICALS, INC.

MDGL|558868105

1993687(+0.0%)

Value:

$660.4B(+7.3%)

ARGENX SE

ARGX|04016X101

673497(+0.0%)

Value:

$398.6B(-3.8%)

PTC THERAPEUTICS, INC.

PTCT|69366J200

7483127(+1.2%)

Value:

$381.3B(+14.3%)

Natera, Inc.

NTRA|632307104

2593546(+0.0%)

Value:

$366.8B(-10.7%)

Axsome Therapeutics, Inc.

AXSM|05464T104

2922729(-27.9%)

Value:

$340.9B(-0.6%)

Akero Therapeutics, Inc.

AKRO|00973Y108

7419340(+8.2%)

Value:

$300.3B(+57.4%)

Protagonist Therapeutics, Inc

PTGX|74366E102

5719415(+4.0%)

Value:

$276.6B(+30.3%)

Avidity Biosciences, Inc.

RNA|05370A108

8746926(+10.3%)

Value:

$258.2B(+11.9%)

Penumbra Inc

PEN|70975L107

862770(+0.0%)

Value:

$230.7B(+12.6%)

INSMED Inc

INSM|457669307

3014558(+0.0%)

Value:

$230.0B(+10.5%)

Alkermes plc.

ALKS|G01767105

6884698(-8.9%)

Value:

$227.3B(+4.6%)

STRYKER CORP

SYK|863667101

590221(+0.0%)

Value:

$219.7B(+3.4%)

Verona Pharma plc

VRNA|925050106

2848800(+56.4%)

Value:

$180.9B(+113.9%)

Merus N.V.

MRUS|N5749R100

4169393(+0.0%)

Value:

$175.5B(+0.1%)

Tarsus Pharmaceuticals, Inc.

TARS|87650L103

3316032(+2.5%)

Value:

$170.3B(-4.9%)

Immunocore Holdings plc

IMCR|45258D105

4869798(+0.0%)

Value:

$144.5B(+0.6%)

ACADIA PHARMACEUTICALS INC

ACAD|004225108

8540117(-1.9%)

Value:

$141.9B(-11.2%)

ROCKET PHARMACEUTICALS, INC.

RCKT|77313F106

17687772(+0.0%)

Value:

$118.0B(-46.9%)

RadNet, Inc.

RDNT|750491102

2317582(+17.1%)

Value:

$115.2B(-16.6%)

MASIMO CORP

MASI|574795100

683294(+0.0%)

Value:

$113.8B(+0.8%)

Instrument	Shares		Other Manager	Value
Madrigal Pharmaceuticals, Inc.(MDGLcusip558868105)	2.0M	QoQ 0.00% (+0) YoY +402.12% (+1.6M)	All Managers (Combined)	$660.4M	QoQ +7.34% (+$45.2M) YoY +522.82% (+$554.3M)
Argenx Se(ARGXcusip04016X101)	673.5K	QoQ 0.00% (-0) YoY +0.94% (+6.3K)	All Managers (Combined)	$398.6M	QoQ -3.76% (-$15.6M) YoY +51.74% (+$135.9M)
Ptc Therapeutics, Inc.(PTCTcusip69366J200)	7.5M	QoQ +1.21% (+90.0K) YoY +0.79% (+59.2K)	All Managers (Combined)	$381.3M	QoQ +14.26% (+$47.6M) YoY +76.57% (+$165.4M)
Natera, Inc.(NTRAcusip632307104)	2.6M	QoQ 0.00% (-223) YoY 0.00% (+223)	All Managers (Combined)	$366.8M	QoQ -10.66% (-$43.8M) YoY +54.62% (+$129.6M)
Axsome Therapeutics, Inc.(AXSMcusip05464T104)	2.9M	QoQ -27.85% (-1.1M) YoY -34.94% (-1.6M)	All Managers (Combined)	$340.9M	QoQ -0.55% (-$1.9M) YoY -4.91% (-$17.6M)
Akero Therapeutics, Inc.(AKROcusip00973Y108)	7.4M	QoQ +8.15% (+559.5K) YoY +36.58% (+2.0M)	All Managers (Combined)	$300.3M	QoQ +57.37% (+$109.5M) YoY +118.88% (+$163.1M)
Protagonist Therapeutics, Inc(PTGXcusip74366E102)	5.7M	QoQ +4.01% (+220.9K) YoY +7.59% (+403.9K)	All Managers (Combined)	$276.6M	QoQ +30.31% (+$64.3M) YoY +79.86% (+$122.8M)
Avidity Biosciences, Inc.(RNAcusip05370A108)	8.7M	QoQ +10.26% (+814.1K) YoY +9.74% (+776.7K)	All Managers (Combined)	$258.2M	QoQ +11.93% (+$27.5M) YoY +26.94% (+$54.8M)
Penumbra Inc(PENcusip70975L107)	862.8K	QoQ +0.03% (+320) YoY +27.64% (+186.9K)	All Managers (Combined)	$230.7M	QoQ +12.64% (+$25.9M) YoY +52.94% (+$79.9M)
Insmed Inc(INSMcusip457669307)	3.0M	QoQ 0.00% (+0) YoY +61.62% (+1.1M)	All Managers (Combined)	$230.0M	QoQ +10.50% (+$21.9M) YoY +354.50% (+$179.4M)
Alkermes Plc.(ALKScusipG01767105)	6.9M	QoQ -8.90% (-673.1K) YoY +13.71% (+830.4K)	All Managers (Combined)	$227.3M	QoQ +4.58% (-$10.0M) YoY +38.71% (+$63.4M)
Stryker Corp(SYKcusip863667101)	590.2K	QoQ 0.00% (+0) YoY +83.86% (+269.2K)	All Managers (Combined)	$219.7M	QoQ +3.38% (+$7.2M) YoY +91.25% (+$104.8M)
Verona Pharma Plc(VRNAcusip925050106)	2.8M	QoQ +56.43% (+1.0M) YoY NEW(+2.8M)	All Managers (Combined)	$180.9M	QoQ +113.87% (+$96.3M) YoY NEW(+$180.9M)
Merus N.V.(MRUScusipN5749R100)	4.2M	QoQ 0.00% (+0) YoY +1.46% (-60.0K)	All Managers (Combined)	$175.5M	QoQ +0.09% (+$166.8K) YoY -5.16% (-$9.6M)
Tarsus Pharmaceuticals, Inc.(TARScusip87650L103)	3.3M	QoQ +2.45% (-79.5K) YoY +1.33% (+43.7K)	All Managers (Combined)	$170.3M	QoQ -4.94% (-$8.9M) YoY +43.20% (+$51.4M)
Immunocore Holdings Plc(IMCRcusip45258D105)	4.9M	QoQ 0.00% (+0) YoY -19.10% (-1.1M)	All Managers (Combined)	$144.5M	QoQ +0.57% (+$827.9K) YoY -63.07% (-$246.8M)
Acadia Pharmaceuticals Inc(ACADcusip004225108)	8.5M	QoQ -1.89% (-165.4K) YoY -38.24% (-5.3M)	All Managers (Combined)	$141.9M	QoQ -11.20% (-$17.9M) YoY -44.52% (-$113.9M)
Rocket Pharmaceuticals, Inc.(RCKTcusip77313F106)	17.7M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$118.0M	QoQ -46.93% (-$104.4M) YoY -75.24% (-$358.5M)
Radnet, Inc.(RDNTcusip750491102)	2.3M	QoQ +17.13% (-339.0K) YoY +36.28% (+617.0K)	All Managers (Combined)	$115.2M	QoQ -16.61% (-$23.0M) YoY +39.25% (+$32.5M)
Masimo Corp(MASIcusip574795100)	683.3K	QoQ 0.00% (+0) YoY -53.27% (-779.1K)	All Managers (Combined)	$113.8M	QoQ +0.78% (+$888.3K) YoY -46.99% (-$100.9M)