Sio Capital Management, LLC

Investment Portfolio & 13F Holdings Analysis

About

Type: FundHoldings: 54Value: $335.8MLatest: 2025Q1

Sio Capital Management, LLC is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 54 holdings worth $0.3 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  null,
  "AKRO",
  "ENTA",
  "AORT",
  "ANIP",
  "ANNX",
  "ATXS",
  "SVRA",
  "TVTX",
  "TERN",
  "TYRA",
  "ALGS",
  "ALEC",
  "AVTX",
  "APRE",
  "AVR",
  null,
  "NBIX",
  "MODD",
  "NXTC",
  "OVID",
  "PRQR",
  "PMVP",
  "SEPN",
  "TELA",
  "TARA",
  "IDYA",
  "ICLR",
  "HUMAW",
  "MRK",
  null,
  "PRAX",
  "AQST",
  "SLNO",
  "ETNB",
  "BOLD",
  "GMED",
  "HAE",
  "MMS",
  "CNTX",
  "ERAS",
  "IRWD",
  "VTYX",
  "VXRT",
  "VIR",
  "AVNS",
  "FHTX",
  "LH",
  "EMBC",
  "TFX",
  "ZBH",
  "BMRN",
  "DNTH",
  "IRON"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 54
Total Value: 335797884
Accession Number: 0001214659-25-007756
Form Type: 13F-HR
CIK: sio-capital-management
Manager Name: Sio-Capital-Management

Data Enrichment

94% identified

51 identified3 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

54 positions • $335.8M total value

SEC FilingSEC DataHachi Filing

Manager:

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ICON PLC

ICLR|G4705A100

Shares:203.3K

Value:$35.6M

% of Portfolio:10.6% ($35.6M/$335.8M)

MAXIMUS, INC.

MMS|577933104

Shares:468.4K

Value:$31.9M

% of Portfolio:9.5% ($31.9M/$335.8M)

Merck & Co., Inc.

MRK|58933Y105

Shares:270.6K

Value:$24.3M

% of Portfolio:7.2% ($24.3M/$335.8M)

ZIMMER BIOMET HOLDINGS, INC.

ZBH|98956P102

Shares:187.7K

Value:$21.2M

% of Portfolio:6.3% ($21.2M/$335.8M)

NEUROCRINE BIOSCIENCES INC

NBIX|64125C109

Shares:187.6K

Value:$20.7M

% of Portfolio:6.2% ($20.7M/$335.8M)

LABCORP HOLDINGS INC.

LH|504922105

Shares:83.9K

Value:$19.5M

% of Portfolio:5.8% ($19.5M/$335.8M)

10919W405

Shares:507.6K

Value:$18.3M

% of Portfolio:5.5% ($18.3M/$335.8M)

GLOBUS MEDICAL INC

GMED|379577208

Shares:207.0K

Value:$15.2M

% of Portfolio:4.5% ($15.2M/$335.8M)

TELEFLEX INC

TFX|879369106

Shares:107.8K

Value:$14.9M

% of Portfolio:4.4% ($14.9M/$335.8M)

Embecta Corp.

EMBC|29082K105

Shares:1.1M

Value:$14.1M

% of Portfolio:4.2% ($14.1M/$335.8M)

BIOMARIN PHARMACEUTICAL INC

BMRN|09061G101

Shares:141.1K

Value:$10.0M

% of Portfolio:3.0% ($10.0M/$335.8M)

Anteris Technologies Global Corp.

AVR|03675P102

Shares:2.4M

Value:$8.6M

% of Portfolio:2.6% ($8.6M/$335.8M)

HAEMONETICS CORP

HAE|405024100

Shares:134.0K

Value:$8.5M

% of Portfolio:2.5% ($8.5M/$335.8M)

Annexon, Inc.

ANNX|03589W102

Shares:3.4M

Value:$6.6M

% of Portfolio:2.0% ($6.6M/$335.8M)

Protara Therapeutics, Inc.

TARA|74365U107

Shares:1.5M

Value:$6.5M

% of Portfolio:1.9% ($6.5M/$335.8M)

ANI PHARMACEUTICALS INC

ANIP|00182C103

Shares:87.3K

Value:$5.8M

% of Portfolio:1.7% ($5.8M/$335.8M)

SOLENO THERAPEUTICS INC

SLNO|834203309

Shares:78.3K

Value:$5.6M

% of Portfolio:1.7% ($5.6M/$335.8M)

Septerna, Inc.

SEPN|81734D104

Shares:788.7K

Value:$4.6M

% of Portfolio:1.4% ($4.6M/$335.8M)

Praxis Precision Medicines, Inc.

PRAX|74006W207

Shares:112.5K

Value:$4.3M

% of Portfolio:1.3% ($4.3M/$335.8M)

AVANOS MEDICAL, INC.

AVNS|05350V106

Shares:286.0K

Value:$4.1M

% of Portfolio:1.2% ($4.1M/$335.8M)

Instrument	Shares		Other Manager	Value	% of Portfolio
ICON PLC(ICLRcusipG4705A100)	203.3K	QoQ +3.99% (-7.8K) YoY NEW(+203.3K)	All Managers (Combined)	$35.6M	10.6% ($35.6M/$335.8M)	QoQ -13.22% (-$5.4M) YoY NEW(+$35.6M)
MAXIMUS, INC.(MMScusip577933104)	468.4K	QoQ +22.79% (+86.9K) YoY NEW(+468.4K)	All Managers (Combined)	$31.9M	9.5% ($31.9M/$335.8M)	QoQ +12.16% (+$3.5M) YoY NEW(+$31.9M)
Merck & Co., Inc.(MRKcusip58933Y105)	270.6K	QoQ NEW(+270.6K) YoY NEW(+270.6K)	All Managers (Combined)	$24.3M	7.2% ($24.3M/$335.8M)	QoQ NEW(+$24.3M) YoY NEW(+$24.3M)
ZIMMER BIOMET HOLDINGS, INC.(ZBHcusip98956P102)	187.7K	QoQ +7.36% (+12.9K) YoY +153.01% (+113.5K)	All Managers (Combined)	$21.2M	6.3% ($21.2M/$335.8M)	QoQ +15.03% (+$2.8M) YoY +116.97% (+$11.5M)
NEUROCRINE BIOSCIENCES INC(NBIXcusip64125C109)	187.6K	QoQ NEW(+187.6K) YoY NEW(+187.6K)	All Managers (Combined)	$20.7M	6.2% ($20.7M/$335.8M)	QoQ NEW(+$20.7M) YoY NEW(+$20.7M)
LABCORP HOLDINGS INC.(LHcusip504922105)	83.9K	QoQ -25.96% (-29.4K) YoY NEW(+83.9K)	All Managers (Combined)	$19.5M	5.8% ($19.5M/$335.8M)	QoQ -24.86% (-$6.5M) YoY NEW(+$19.5M)
(cusip10919W405)✕	507.6K	QoQ +12.34% (+55.8K) YoY NEW(+507.6K)	All Managers (Combined)	$18.3M	5.5% ($18.3M/$335.8M)	QoQ +12.49% (+$2.0M) YoY NEW(+$18.3M)
GLOBUS MEDICAL INC(GMEDcusip379577208)	207.0K	QoQ NEW(+207.0K) YoY -47.38% (-186.4K)	All Managers (Combined)	$15.2M	4.5% ($15.2M/$335.8M)	QoQ NEW(+$15.2M) YoY -28.19% (-$6.0M)
TELEFLEX INC(TFXcusip879369106)	107.8K	QoQ +61.41% (+41.0K) YoY +218.14% (+73.9K)	All Managers (Combined)	$14.9M	4.4% ($14.9M/$335.8M)	QoQ +25.32% (+$3.0M) YoY +94.38% (+$7.2M)
Embecta Corp.(EMBCcusip29082K105)	1.1M	QoQ +160.26% (+682.0K) YoY +89.20% (+522.2K)	All Managers (Combined)	$14.1M	4.2% ($14.1M/$335.8M)	QoQ +60.69% (+$5.3M) YoY +81.78% (+$6.4M)
BIOMARIN PHARMACEUTICAL INC(BMRNcusip09061G101)	141.1K	QoQ NEW(+141.1K) YoY NEW(+141.1K)	All Managers (Combined)	$10.0M	3.0% ($10.0M/$335.8M)	QoQ NEW(+$10.0M) YoY NEW(+$10.0M)
Anteris Technologies Global Corp.(AVRcusip03675P102)	2.4M	QoQ 0.00% (-40) YoY NEW(+2.4M)	All Managers (Combined)	$8.6M	2.6% ($8.6M/$335.8M)	QoQ -34.76% (-$4.6M) YoY NEW(+$8.6M)
HAEMONETICS CORP(HAEcusip405024100)	134.0K	QoQ NEW(+134.0K) YoY NEW(+134.0K)	All Managers (Combined)	$8.5M	2.5% ($8.5M/$335.8M)	QoQ NEW(+$8.5M) YoY NEW(+$8.5M)
Annexon, Inc.(ANNXcusip03589W102)	3.4M	QoQ +43.54% (-1.0M) YoY NEW(+3.4M)	All Managers (Combined)	$6.6M	2.0% ($6.6M/$335.8M)	QoQ -45.99% (-$5.6M) YoY NEW(+$6.6M)
Protara Therapeutics, Inc.(TARAcusip74365U107)	1.5M	QoQ +5.34% (-76.8K) YoY NEW(+1.5M)	All Managers (Combined)	$6.5M	1.9% ($6.5M/$335.8M)	QoQ -15.00% (-$1.1M) YoY NEW(+$6.5M)
ANI PHARMACEUTICALS INC(ANIPcusip00182C103)	87.3K	QoQ -45.45% (-72.8K) YoY -0.06% (-56)	All Managers (Combined)	$5.8M	1.7% ($5.8M/$335.8M)	QoQ -33.94% (-$3.0M) YoY -3.21% (-$194.2K)
SOLENO THERAPEUTICS INC(SLNOcusip834203309)	78.3K	QoQ NEW(+78.3K) YoY NEW(+78.3K)	All Managers (Combined)	$5.6M	1.7% ($5.6M/$335.8M)	QoQ NEW(+$5.6M) YoY NEW(+$5.6M)
Septerna, Inc.(SEPNcusip81734D104)	788.7K	QoQ +190.28% (-517.0K) YoY NEW(+788.7K)	All Managers (Combined)	$4.6M	1.4% ($4.6M/$335.8M)	QoQ -26.60% (-$1.7M) YoY NEW(+$4.6M)
Praxis Precision Medicines, Inc.(PRAXcusip74006W207)	112.5K	QoQ NEW(+112.5K) YoY NEW(+112.5K)	All Managers (Combined)	$4.3M	1.3% ($4.3M/$335.8M)	QoQ NEW(+$4.3M) YoY NEW(+$4.3M)
AVANOS MEDICAL, INC.(AVNScusip05350V106)	286.0K	QoQ NEW(+286.0K) YoY NEW(+286.0K)	All Managers (Combined)	$4.1M	1.2% ($4.1M/$335.8M)	QoQ NEW(+$4.1M) YoY NEW(+$4.1M)