Sphera Funds Management Ltd.

Investment Portfolio & 13F Holdings Analysis

About

SPHERA FUNDS MANAGEMENT LTD. is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 114 holdings worth $0.4 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "NVMI",
  "MRUS",
  "ORIC",
  "NTR",
  "FROG",
  "ABBV",
  "APLS",
  "ARWR",
  "AVGO",
  "NICE",
  "NNDM",
  "SKYE",
  "SWTX",
  "TSEM",
  "RCKT",
  "ARVN",
  "ANNX",
  "ATXS",
  "GPCR",
  "IMTX",
  "CATX",
  "SVRA",
  "TVTX",
  "LRMR",
  "MLYS",
  "PHVS",
  "SNDX",
  "ALEC",
  "JANX",
  "APRE",
  "APLT",
  "AZN",
  "SRRK",
  "FATE",
  "AMAT",
  "JSPR",
  "META",
  "LVTX",
  null,
  "OTLK",
  "OKUR",
  "SEDG",
  "IONS",
  "PMN",
  "CYBN",
  null,
  "RZLT",
  "MRVL",
  "ACOG",
  "MSFT",
  "NVS",
  "TEVA",
  "ZURA",
  null,
  "NVDA",
  "PFE",
  "MRK",
  "AMGN",
  null,
  "ORA",
  null,
  "UBER",
  "RNA",
  "PRAX",
  "RGLS",
  "NTLA",
  "PERI",
  "COGT",
  "ETNB",
  "DYN",
  "SNY",
  "GSK",
  "SRPT",
  null,
  null,
  null,
  "CRVS",
  "CDTX",
  "ELDN",
  "ELEV",
  "ELVN",
  "INZY",
  "KURA",
  "KZR",
  "NVO",
  "AMZN",
  null,
  "VTYX",
  "VTGN",
  "VKTX",
  "VIR",
  "VIGL",
  "HOWL",
  "WIX",
  "WDAY",
  "XENE",
  "BIIB",
  "CHKP",
  "BHVN",
  "RARE",
  "CRM",
  "IMVT",
  "BMY",
  "BBIO",
  "CAMT",
  "CEVA",
  "CLDX",
  "DAWN",
  "CYTK",
  "NKE",
  "GOOG",
  "JNJ",
  "LLY"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 114
Total Value: 419305182
Accession Number: 0001496201-25-000007
Form Type: 13F-HR
CIK: sphera-funds-management
Manager Name: Sphera-Funds-Management

Data Enrichment

92% identified

105 identified9 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

114 positions • $419,305.182K total value

114 positions

Manager:

SEC FilingSEC DataHachi Filing

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TEVA PHARMACEUTICAL INDUSTRIES LTD

TEVA|881624209

Shares:1.6M

Value:$24.2M

464287432

Shares:255.1K

Value:$23.2M

Syndax Pharmaceuticals Inc

SNDX|87164F105

Shares:1.7M

Value:$20.4M

Sanofi

SNY|80105N105

Shares:304.5K

Value:$16.9M

NOVA LTD.

NVMI|M7516K103

Shares:90.7K

Value:$16.7M

ASTRAZENECA PLC

AZN|046353108

Shares:175.1K

Value:$12.9M

BridgeBio Pharma, Inc.

BBIO|10806X102

Shares:366.6K

Value:$12.7M

Sarepta Therapeutics, Inc.

SRPT|803607100

Shares:157.9K

Value:$10.1M

ELI LILLY & Co

LLY|532457108

Shares:11.7K

Value:$9.7M

Celldex Therapeutics, Inc.

CLDX|15117B202

Shares:507.8K

Value:$9.2M

JOHNSON & JOHNSON

JNJ|478160104

Shares:52.8K

Value:$8.8M

NOVO NORDISK A S

NVO|670100205

Shares:118.1K

Value:$8.2M

Eledon Pharmaceuticals, Inc.

ELDN|28617K101

Shares:2.3M

Value:$7.8M

Mineralys Therapeutics, Inc.

MLYS|603170101

Shares:465.5K

Value:$7.4M

AMAZON COM INC

AMZN|023135106

Shares:36.6K

Value:$7.0M

AbbVie Inc.

ABBV|00287Y109

Shares:30.3K

Value:$6.3M

Pharvaris N.V.

PHVS|N69605108

Shares:383.9K

Value:$6.0M

ORMAT TECHNOLOGIES, INC.

ORA|686688102

Shares:84.0K

Value:$5.9M

CYTOKINETICS INC

CYTK|23282W605

Shares:145.0K

Value:$5.8M

Meta Platforms, Inc.

META|30303M102

Shares:10.0K

Value:$5.7M

Instrument	Shares		Other Manager	Value
TEVA PHARMACEUTICAL INDUSTRIES LTD(TEVAcusip881624209)	1.6M	QoQ +0.19% (-3.0K) YoY -55.80% (-2.0M)	All Managers (Combined)	$24.2M	QoQ -30.12% (-$10.4M) YoY -51.86% (-$26.0M)
(cusip464287432)✕	255.1K	QoQ NEW(+255.1K) YoY NEW(+255.1K)	All Managers (Combined)	$23.2M	QoQ NEW(+$23.2M) YoY NEW(+$23.2M)
Syndax Pharmaceuticals Inc(SNDXcusip87164F105)	1.7M	QoQ +20.46% (+282.7K) YoY +104.67% (+851.0K)	All Managers (Combined)	$20.4M	QoQ +11.94% (+$2.2M) YoY +5.65% (+$1.1M)
Sanofi(SNYcusip80105N105)	304.5K	QoQ -20.80% (-80.0K) YoY -39.03% (-195.0K)	All Managers (Combined)	$16.9M	QoQ -8.93% (-$1.7M) YoY -30.43% (-$7.4M)
NOVA LTD.(NVMIcusipM7516K103)	90.7K	QoQ +33.09% (+22.6K) YoY +158.35% (+55.6K)	All Managers (Combined)	$16.7M	QoQ +24.56% (+$3.3M) YoY +168.47% (+$10.5M)
ASTRAZENECA PLC(AZNcusip046353108)	175.1K	QoQ -22.21% (-50.0K) YoY -7.89% (-15.0K)	All Managers (Combined)	$12.9M	QoQ -12.74% (-$1.9M) YoY -0.07% (-$9.7K)
BridgeBio Pharma, Inc.(BBIOcusip10806X102)	366.6K	QoQ -59.50% (-538.7K) YoY +633.21% (+316.6K)	All Managers (Combined)	$12.7M	QoQ -48.98% (-$12.2M) YoY +719.76% (+$11.1M)
Sarepta Therapeutics, Inc.(SRPTcusip803607100)	157.9K	QoQ +59.65% (-59.0K) YoY +183.97% (+102.3K)	All Managers (Combined)	$10.1M	QoQ -16.20% (-$1.9M) YoY +39.99% (+$2.9M)
ELI LILLY & Co(LLYcusip532457108)	11.7K	QoQ -11.37% (-1.5K) YoY -17.61% (-2.5K)	All Managers (Combined)	$9.7M	QoQ -5.18% (-$527.8K) YoY -12.54% (-$1.4M)
Celldex Therapeutics, Inc.(CLDXcusip15117B202)	507.8K	QoQ +7.11% (-33.7K) YoY +83.33% (-230.8K)	All Managers (Combined)	$9.2M	QoQ -23.06% (-$2.8M) YoY -20.71% (-$2.4M)
JOHNSON & JOHNSON(JNJcusip478160104)	52.8K	QoQ -24.34% (-17.0K) YoY -33.82% (-27.0K)	All Managers (Combined)	$8.8M	QoQ -13.24% (-$1.3M) YoY -30.62% (-$3.9M)
NOVO NORDISK A S(NVOcusip670100205)	118.1K	QoQ +20.39% (-20.0K) YoY +42.12% (-35.0K)	All Managers (Combined)	$8.2M	QoQ -2.81% (-$237.4K) YoY -23.13% (-$2.5M)
Eledon Pharmaceuticals, Inc.(ELDNcusip28617K101)	2.3M	QoQ -9.58% (-244.5K) YoY NEW(+2.3M)	All Managers (Combined)	$7.8M	QoQ -25.60% (-$2.7M) YoY NEW(+$7.8M)
Mineralys Therapeutics, Inc.(MLYScusip603170101)	465.5K	QoQ +144.15% (+274.9K) YoY -29.33% (-193.3K)	All Managers (Combined)	$7.4M	QoQ +214.95% (+$5.0M) YoY -13.08% (-$1.1M)
AMAZON COM INC(AMZNcusip023135106)	36.6K	QoQ -41.52% (-26.0K) YoY -32.74% (-17.8K)	All Managers (Combined)	$7.0M	QoQ -49.29% (-$6.8M) YoY -29.06% (-$2.9M)
AbbVie Inc.(ABBVcusip00287Y109)	30.3K	QoQ -11.67% (-4.0K) YoY -20.37% (-7.7K)	All Managers (Combined)	$6.3M	QoQ +4.13% (-$251.9K) YoY -8.38% (-$580.6K)
Pharvaris N.V.(PHVScusipN69605108)	383.9K	QoQ -1.11% (-4.3K) YoY -2.29% (-9.0K)	All Managers (Combined)	$6.0M	QoQ -19.01% (-$1.4M) YoY -33.62% (-$3.1M)
ORMAT TECHNOLOGIES, INC.(ORAcusip686688102)	84.0K	QoQ +6.32% (+5.0K) YoY NEW(+84.0K)	All Managers (Combined)	$5.9M	QoQ +11.11% (+$594.8K) YoY NEW(+$5.9M)
CYTOKINETICS INC(CYTKcusip23282W605)	145.0K	QoQ +189.92% (+95.0K) YoY -48.53% (-136.7K)	All Managers (Combined)	$5.8M	QoQ +147.70% (+$3.5M) YoY -70.49% (-$13.9M)
Meta Platforms, Inc.(METAcusip30303M102)	10.0K	QoQ -52.56% (-11.0K) YoY -60.83% (-15.5K)	All Managers (Combined)	$5.7M	QoQ -53.30% (-$6.6M) YoY -53.51% (-$6.6M)