Vr Adviser, LLC

Investment Portfolio & 13F Holdings Analysis

About

VR Adviser, LLC is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 37 holdings worth $1.2 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

AI_NATIVE detailed information: This accession holds the following tickers:[
  "OCUL",
  "TRVI",
  "ORIC",
  "TIL",
  "ABVX",
  "ATXS",
  "SVRA",
  "PHVS",
  "ARTV",
  "APLT",
  null,
  "SYRE",
  "APGE",
  "KALV",
  "MRSN",
  null,
  "TNYA",
  "SRZN",
  "ZURA",
  null,
  "UPB",
  "SLDB",
  "PRAX",
  "FDMT",
  "TENX",
  "COGT",
  "DYN",
  "GLYC",
  null,
  "CDTX",
  "ERAS",
  "ELVN",
  "VRDN",
  "ORKA",
  "IPSC",
  "CGEM",
  "DNTH"
]

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 37
Total Value: 1175247364
Accession Number: 0001415889-25-013093
Form Type: 13F-HR
CIK: vr-adviser
Manager Name: Vr-Adviser

Data Enrichment

89% identified

33 identified4 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

37 positions • $1,175,247.364K total value

37 positions

Manager:

SEC FilingSEC DataHachi Filing

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Apogee Therapeutics, Inc.

APGE|03770N101

Shares:8.5M

Value:$317.3M

59267L107

Shares:3.8M

Value:$102.1M

OCULAR THERAPEUTIX, INC

OCUL|67576A100

Shares:12.8M

Value:$93.5M

Enliven Therapeutics, Inc.

ELVN|29337E102

Shares:4.0M

Value:$79.2M

KalVista Pharmaceuticals, Inc.

KALV|483497103

Shares:6.7M

Value:$77.4M

Viridian Therapeutics, Inc.\DE

VRDN|92790C104

Shares:3.9M

Value:$52.3M

Pharvaris N.V.

PHVS|N69605108

Shares:3.1M

Value:$48.9M

Spyre Therapeutics, Inc.

SYRE|00773J202

Shares:2.7M

Value:$43.3M

Oruka Therapeutics, Inc.

ORKA|687604108

Shares:4.1M

Value:$42.6M

Praxis Precision Medicines, Inc.

PRAX|74006W207

Shares:990.0K

Value:$37.5M

Cogent Biosciences, Inc.

COGT|19240Q201

Shares:5.7M

Value:$34.0M

Dianthus Therapeutics, Inc. /DE/

DNTH|252828108

Shares:1.7M

Value:$31.6M

Dyne Therapeutics, Inc.

DYN|26818M108

Shares:2.2M

Value:$22.7M

Cidara Therapeutics, Inc.

CDTX|171757206

Shares:1.1M

Value:$22.6M

29286M105

Shares:5.0M

Value:$22.6M

Erasca, Inc.

ERAS|29479A108

Shares:16.2M

Value:$22.2M

Oric Pharmaceuticals, Inc.

ORIC|68622P109

Shares:3.2M

Value:$17.8M

Upstream Bio, Inc.

UPB|91678A107

Shares:2.3M

Value:$14.0M

Astria Therapeutics, Inc.

ATXS|04635X102

Shares:2.5M

Value:$13.1M

Cullinan Therapeutics, Inc.

CGEM|230031106

Shares:1.4M

Value:$10.4M

Instrument	Shares		Other Manager	Value
Apogee Therapeutics, Inc.(APGEcusip03770N101)	8.5M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$317.3M	QoQ -17.52% (-$67.4M) YoY -43.77% (-$247.1M)
(cusip59267L107)✕	3.8M	QoQ NEW(+3.8M) YoY NEW(+3.8M)	All Managers (Combined)	$102.1M	QoQ NEW(+$102.1M) YoY NEW(+$102.1M)
OCULAR THERAPEUTIX, INC(OCULcusip67576A100)	12.8M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$93.5M	QoQ -14.16% (-$15.4M) YoY -19.45% (-$22.6M)
Enliven Therapeutics, Inc.(ELVNcusip29337E102)	4.0M	QoQ 0.00% (-0) YoY 0.00% (+0)	All Managers (Combined)	$79.2M	QoQ -12.53% (-$11.4M) YoY +11.88% (+$8.4M)
KalVista Pharmaceuticals, Inc.(KALVcusip483497103)	6.7M	QoQ +7.26% (+454.3K) YoY +7.26% (+454.3K)	All Managers (Combined)	$77.4M	QoQ +46.14% (+$24.4M) YoY +4.37% (+$3.2M)
Viridian Therapeutics, Inc.\DE(VRDNcusip92790C104)	3.9M	QoQ 0.00% (-0) YoY 0.00% (-38)	All Managers (Combined)	$52.3M	QoQ -29.68% (-$22.1M) YoY -23.01% (-$15.6M)
Pharvaris N.V.(PHVScusipN69605108)	3.1M	QoQ -3.33% (-107.4K) YoY -8.33% (-282.9K)	All Managers (Combined)	$48.9M	QoQ -20.83% (-$12.9M) YoY -37.72% (-$29.6M)
Spyre Therapeutics, Inc.(SYREcusip00773J202)	2.7M	QoQ 0.00% (-0) YoY +23.65% (-513.7K)	All Managers (Combined)	$43.3M	QoQ -30.69% (-$19.2M) YoY -47.39% (-$39.0M)
Oruka Therapeutics, Inc.(ORKAcusip687604108)	4.1M	QoQ +26.26% (-862.8K) YoY NEW(+4.1M)	All Managers (Combined)	$42.6M	QoQ -33.19% (-$21.1M) YoY NEW(+$42.6M)
Praxis Precision Medicines, Inc.(PRAXcusip74006W207)	990.0K	QoQ 0.00% (-0) YoY +40.19% (-283.9K)	All Managers (Combined)	$37.5M	QoQ -50.79% (-$38.7M) YoY -12.98% (-$5.6M)
Cogent Biosciences, Inc.(COGTcusip19240Q201)	5.7M	QoQ 0.00% (-0) YoY +10.82% (-555.2K)	All Managers (Combined)	$34.0M	QoQ -23.20% (-$10.3M) YoY -1.21% (-$418.4K)
Dianthus Therapeutics, Inc. /DE/(DNTHcusip252828108)	1.7M	QoQ 0.00% (-0) YoY -16.71% (-350.0K)	All Managers (Combined)	$31.6M	QoQ -16.78% (-$6.4M) YoY -49.63% (-$31.2M)
Dyne Therapeutics, Inc.(DYNcusip26818M108)	2.2M	QoQ 0.00% (-0) YoY 0.00% (-0)	All Managers (Combined)	$22.7M	QoQ -55.60% (-$28.5M) YoY -63.15% (-$39.0M)
Cidara Therapeutics, Inc.(CDTXcusip171757206)	1.1M	QoQ +37.32% (+285.8K) YoY NEW(+1.1M)	All Managers (Combined)	$22.6M	QoQ +10.04% (+$2.1M) YoY NEW(+$22.6M)
(cusip29286M105)✕	5.0M	QoQ 0.00% (-0) YoY +96.67% (-2.5M)	All Managers (Combined)	$22.6M	QoQ -32.63% (-$11.0M) YoY -48.01% (-$20.9M)
Erasca, Inc.(ERAScusip29479A108)	16.2M	QoQ 0.00% (-0) YoY NEW(+16.2M)	All Managers (Combined)	$22.2M	QoQ -45.41% (-$18.5M) YoY NEW(+$22.2M)
Oric Pharmaceuticals, Inc.(ORICcusip68622P109)	3.2M	QoQ -27.57% (-1.2M) YoY -27.57% (-1.2M)	All Managers (Combined)	$17.8M	QoQ -49.92% (-$17.7M) YoY -70.61% (-$42.7M)
Upstream Bio, Inc.(UPBcusip91678A107)	2.3M	QoQ 0.00% (-0) YoY NEW(+2.3M)	All Managers (Combined)	$14.0M	QoQ -62.77% (-$23.7M) YoY NEW(+$14.0M)
Astria Therapeutics, Inc.(ATXScusip04635X102)	2.5M	QoQ 0.00% (-0) YoY -31.90% (-1.2M)	All Managers (Combined)	$13.1M	QoQ -40.26% (-$8.8M) YoY -74.16% (-$37.7M)
Cullinan Therapeutics, Inc.(CGEMcusip230031106)	1.4M	QoQ 0.00% (-0) YoY NEW(+1.4M)	All Managers (Combined)	$10.4M	QoQ -37.84% (-$6.4M) YoY NEW(+$10.4M)