Perceptive Advisors LLC

Investment Portfolio & 13F Holdings Analysis

About

PERCEPTIVE ADVISORS LLC is an institutional investment manager that filed its latest Form 13F for 2025Q1, reporting 86 holdings worth $2.7 billion. Form 13F filings provide transparency into the equity holdings of institutional investment managers with over $100 million in assets under management. This page displays the most recent portfolio holdings, allowing investors to track position changes, new investments, and portfolio composition.

Filing Details

13F-HR • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-15
Total Holdings: 86
Total Value: 2694161578
Accession Number: 0001012975-25-000242
Form Type: 13F-HR
CIK: 0001224962
Manager Name: Perceptive Advisors LLC

Data Enrichment

87% identified

75 identified11 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

86 positions • $2,694,161.578K total value

86 positions

Manager:

SEC FilingSEC DataHachi Filing

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Verona Pharma plc

VRNA|925050106

6563340(+2.7%)

Value:

$416.7B(+40.4%)

Arcellx, Inc.

ACLX|03940C100

2926478(-15.9%)

Value:

$192.0B(-28.0%)

AMICUS THERAPEUTICS, INC.

FOLD|03152W109

21464527(-11.5%)

Value:

$175.2B(-23.3%)

RHYTHM PHARMACEUTICALS, INC.

RYTM|76243J105

2548445(-30.8%)

Value:

$135.0B(-34.5%)

Nuvalent, Inc.

NUVL|670703107

1633968(-37.6%)

Value:

$115.9B(-43.5%)

SOLENO THERAPEUTICS INC

SLNO|834203309

1506602(+0.4%)

Value:

$107.6B(+59.5%)

46116X101

786358(-39.0%)

Value:

$103.7B(-3.6%)

MeiraGTx Holdings plc

MGTX|G59665102

12581103(+0.0%)

Value:

$85.3B(+11.3%)

ARTIVION, INC.

AORT|228903100

2793703(+0.0%)

Value:

$68.7B(-14.0%)

Aldeyra Therapeutics, Inc.

ALDX|01438T106

9275851(+0.0%)

Value:

$53.3B(+15.2%)

Protagonist Therapeutics, Inc

PTGX|74366E102

1091271(-14.2%)

Value:

$52.8B(+7.5%)

Evolus, Inc.

EOLS|30052C107

4129142(-19.8%)

Value:

$49.7B(-12.6%)

Immunovant, Inc.

IMVT|45258J102

2844072(+33.0%)

Value:

$48.6B(-8.3%)

Solid Biosciences Inc.

SLDB|83422E204

11906646(+72.4%)

Value:

$44.1B(+59.5%)

Centessa Pharmaceuticals plc

CNTA|152309100

3040395(-52.1%)

Value:

$43.7B(-58.9%)

IOVANCE BIOTHERAPEUTICS, INC.

IOVA|462260100

12711788(-42.5%)

Value:

$42.3B(-74.1%)

Immatics N.V.

IMTX|N44445109

9383456(+0.0%)

Value:

$42.3B(-36.6%)

Apogee Therapeutics, Inc.

APGE|03770N101

1122767(+7.2%)

Value:

$41.9B(-11.6%)

Axsome Therapeutics, Inc.

AXSM|05464T104

355107(-46.5%)

Value:

$41.4B(-26.3%)

INSMED Inc

INSM|457669307

509300(+253.7%)

Value:

$38.9B(+290.8%)

Instrument	Shares		Other Manager	Value
Verona Pharma Plc(VRNAcusip925050106)	6.6M	QoQ +2.67% (+171.2K) YoY +74.48% (+2.8M)	All Managers (Combined)	$416.7M	QoQ +40.37% (+$119.9M) YoY +588.50% (+$356.2M)
Arcellx, Inc.(ACLXcusip03940C100)	2.9M	QoQ -15.87% (-552.4K) YoY -25.60% (-1.0M)	All Managers (Combined)	$192.0M	QoQ -28.04% (-$74.8M) YoY -29.82% (-$81.6M)
Amicus Therapeutics, Inc.(FOLDcusip03152W109)	21.5M	QoQ -11.47% (-2.8M) YoY -23.49% (-6.6M)	All Managers (Combined)	$175.2M	QoQ -23.31% (-$53.2M) YoY -47.00% (-$155.4M)
Rhythm Pharmaceuticals, Inc.(RYTMcusip76243J105)	2.5M	QoQ -30.75% (-1.1M) YoY -22.03% (-720.1K)	All Managers (Combined)	$135.0M	QoQ -34.48% (-$71.0M) YoY -4.68% (-$6.6M)
Nuvalent, Inc.(NUVLcusip670703107)	1.6M	QoQ -37.63% (-986.0K) YoY -41.29% (-1.1M)	All Managers (Combined)	$115.9M	QoQ -43.49% (-$89.2M) YoY -44.55% (-$93.1M)
Soleno Therapeutics Inc(SLNOcusip834203309)	1.5M	QoQ +0.37% (+5.6K) YoY -50.99% (-1.6M)	All Managers (Combined)	$107.6M	QoQ +59.54% (+$40.2M) YoY -18.19% (-$23.9M)
(cusip46116X101)✕	786.4K	QoQ -38.96% (-502.0K) YoY -25.48% (-269.0K)	All Managers (Combined)	$103.7M	QoQ -3.59% (-$3.9M) YoY +42.04% (-$30.7M)
Meiragtx Holdings Plc(MGTXcusipG59665102)	12.6M	QoQ 0.00% (+0) YoY +11.03% (+1.3M)	All Managers (Combined)	$85.3M	QoQ +11.32% (+$8.7M) YoY +24.05% (+$16.5M)
Artivion, Inc.(AORTcusip228903100)	2.8M	QoQ 0.00% (-0) YoY +4.67% (+124.7K)	All Managers (Combined)	$68.7M	QoQ -14.02% (-$11.2M) YoY +21.59% (+$12.2M)
Aldeyra Therapeutics, Inc.(ALDXcusip01438T106)	9.3M	QoQ 0.00% (+0) YoY +7.93% (+682.3K)	All Managers (Combined)	$53.3M	QoQ +15.23% (+$7.0M) YoY +89.80% (+$25.2M)
Protagonist Therapeutics, Inc(PTGXcusip74366E102)	1.1M	QoQ -14.18% (-180.4K) YoY +9.75% (+96.9K)	All Managers (Combined)	$52.8M	QoQ +7.51% (-$3.7M) YoY +83.46% (+$24.0M)
Evolus, Inc.(EOLScusip30052C107)	4.1M	QoQ -19.75% (-1.0M) YoY -28.23% (-1.6M)	All Managers (Combined)	$49.7M	QoQ -12.56% (-$7.1M) YoY -38.33% (-$30.9M)
Immunovant, Inc.(IMVTcusip45258J102)	2.8M	QoQ +32.95% (-704.9K) YoY +2744.07% (+2.7M)	All Managers (Combined)	$48.6M	QoQ -8.27% (-$4.4M) YoY +1404.33% (+$45.4M)
Solid Biosciences Inc.(SLDBcusip83422E204)	11.9M	QoQ +72.39% (+5.0M) YoY +72.39% (-5.0M)	All Managers (Combined)	$44.1M	QoQ +59.46% (+$16.4M) YoY -52.11% (-$47.9M)
Centessa Pharmaceuticals Plc(CNTAcusip152309100)	3.0M	QoQ -52.11% (-3.3M) YoY -1.39% (-42.9K)	All Managers (Combined)	$43.7M	QoQ -58.88% (-$62.6M) YoY +25.48% (-$8.9M)
Iovance Biotherapeutics, Inc.(IOVAcusip462260100)	12.7M	QoQ -42.51% (-9.4M) YoY -34.04% (-6.6M)	All Managers (Combined)	$42.3M	QoQ -74.13% (-$121.3M) YoY -85.17% (-$243.3M)
Immatics N.V.(IMTXcusipN44445109)	9.4M	QoQ 0.00% (-0) YoY +104.77% (-4.8M)	All Managers (Combined)	$42.3M	QoQ -36.56% (-$24.4M) YoY -12.12% (-$5.8M)
Apogee Therapeutics, Inc.(APGEcusip03770N101)	1.1M	QoQ +7.21% (-75.5K) YoY -45.50% (-937.6K)	All Managers (Combined)	$41.9M	QoQ -11.57% (-$5.5M) YoY -69.36% (-$95.0M)
Axsome Therapeutics, Inc.(AXSMcusip05464T104)	355.1K	QoQ -46.52% (-309.0K) YoY -67.87% (-750.2K)	All Managers (Combined)	$41.4M	QoQ -26.28% (-$14.8M) YoY -53.04% (-$46.8M)
Insmed Inc(INSMcusip457669307)	509.3K	QoQ +253.68% (+365.3K) YoY NEW(+509.3K)	All Managers (Combined)	$38.9M	QoQ +290.82% (+$28.9M) YoY NEW(+$38.9M)