Siren

AI_NATIVE detailed information: This accession holds the following tickers:[
  "MRUS",
  "ASND",
  "EWTX",
  "TRVI",
  "CNTA",
  "NAMS",
  "RVMD",
  "ORIC",
  "TIL",
  "PCOR",
  "INFA",
  "EDU",
  "FROG",
  "ADBE",
  "APLS",
  "ARWR",
  "GOOGL",
  "GDS",
  "CRBU",
  "DT",
  "RCKT",
  "BCAX",
  "BCYC",
  "RCUS",
  "TNGX",
  "SLN",
  "RAPP",
  "IGMS",
  "TSHA",
  "TRML",
  "STOK",
  "SMMT",
  "KYMR",
  "NMRA",
  "PRTA",
  "AGEN",
  "BIOA",
  "QCOM",
  "SRRK",
  "SYRE",
  "APGE",
  "KRRO",
  "LXEO",
  null,
  "PRQR",
  "SEER",
  "SGMT",
  "SEMR",
  "SEPN",
  "SARO",
  "WHWK",
  "IONQ",
  "CYCN",
  "MRVL",
  "MSFT",
  "OXY",
  "PANW",
  "PYPL",
  "NVDA",
  "INTC",
  "LPLA",
  "MDB",
  "RELY",
  "NOW",
  "UPB",
  null,
  "RNA",
  "TBLA",
  "SLDB",
  "LXRX",
  "RYTM",
  "SLNO",
  "RNAC",
  "DYN",
  null,
  "GOSS",
  "TSM",
  "WVE",
  "DECK",
  "ELDN",
  "ERAS",
  "GBIO",
  "IHS",
  "HOOK",
  "KLRS",
  "IRWD",
  "KRON",
  "RACE",
  "AMZN",
  "BEKE",
  "PDD",
  "USB",
  "VIGL",
  "WK",
  "XENE",
  null,
  "FHTX",
  "VERA",
  "CRM",
  "RDDT",
  "PEGA",
  "PCVX",
  null,
  "BDTX",
  "BILL",
  "BPMC",
  "BA",
  "BASE",
  "CRNX",
  "CRWD",
  "CGEM",
  "DDOG",
  "DNLI",
  "IRON",
  "NKE",
  "TSLA"
]

Filing Details

13F-HR/A • 2025-03-31

SEC FilingSEC DataHachi Filing

Report Date: 2025-03-31
Filing Date: 2025-05-23
Total Holdings: 117
Total Value: 1772780355
Accession Number: 0002005245-25-000008
Form Type: 13F-HR/A
CIK: siren
Manager Name: Siren

Data Enrichment

96% identified

112 identified5 unidentified

Holdings

SEC FilingSEC DataHachi Filing

Manager:

117 positions • $1.8B total value

SEC FilingSEC DataHachi Filing

Manager:

Search and click to pin securities to the top

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Taysha Gene Therapies, Inc.

TSHA|877619106

Shares:6.5M

Value:$9.1M

% of Portfolio:0.5% ($9.1M/$1.8B)

Cullinan Therapeutics, Inc.

CGEM|230031106

Shares:1.2M

Value:$9.0M

% of Portfolio:0.5% ($9.0M/$1.8B)

CrowdStrike Holdings, Inc.

CRWD|22788C105

Shares:25.0K

Value:$8.8M

% of Portfolio:0.5% ($8.8M/$1.8B)

Silence Therapeutics plc

SLN|82686Q101

Shares:2.8M

Value:$7.9M

% of Portfolio:0.4% ($7.9M/$1.8B)

Alphabet Inc.

GOOGL|02079K305

Shares:50.7K

Value:$7.8M

% of Portfolio:0.4% ($7.8M/$1.8B)

Cartesian Therapeutics, Inc.

RNAC|816212302

Shares:563.3K

Value:$7.4M

% of Portfolio:0.4% ($7.4M/$1.8B)

ADOBE INC.

ADBE|00724F101

Shares:19.3K

Value:$7.4M

% of Portfolio:0.4% ($7.4M/$1.8B)

Korro Bio, Inc.

KRRO|500946108

Shares:418.8K

Value:$7.3M

% of Portfolio:0.4% ($7.3M/$1.8B)

ServiceNow, Inc.

NOW|81762P102

Shares:9.1K

Value:$7.3M

% of Portfolio:0.4% ($7.3M/$1.8B)

Seer, Inc.

SEER|81578P106

Shares:4.0M

Value:$6.8M

% of Portfolio:0.4% ($6.8M/$1.8B)

PDD Holdings Inc.

PDD|722304102

Shares:52.9K

Value:$6.3M

% of Portfolio:0.4% ($6.3M/$1.8B)

Spyre Therapeutics, Inc.

SYRE|00773J202

Shares:368.6K

Value:$5.9M

% of Portfolio:0.3% ($5.9M/$1.8B)

Gossamer Bio, Inc.

GOSS|38341P102

Shares:5.2M

Value:$5.7M

% of Portfolio:0.3% ($5.7M/$1.8B)

Oric Pharmaceuticals, Inc.

ORIC|68622P109

Shares:1.0M

Value:$5.6M

% of Portfolio:0.3% ($5.6M/$1.8B)

Upstream Bio, Inc.

UPB|91678A107

Shares:788.5K

Value:$4.8M

% of Portfolio:0.3% ($4.8M/$1.8B)

NVIDIA CORP

NVDA|67066G104

Shares:44.4K

Value:$4.8M

% of Portfolio:0.3% ($4.8M/$1.8B)

TAIWAN SEMICONDUCTOR MANUFACTURING CO LTD

TSM|874039100

Shares:28.5K

Value:$4.7M

% of Portfolio:0.3% ($4.7M/$1.8B)

Datadog, Inc.

DDOG|23804L103

Shares:47.4K

Value:$4.7M

% of Portfolio:0.3% ($4.7M/$1.8B)

Neumora Therapeutics, Inc.

NMRA|640979100

Shares:4.4M

Value:$4.4M

% of Portfolio:0.2% ($4.4M/$1.8B)

JFrog Ltd

FROG|M6191J100

Shares:131.6K

Value:$4.2M

% of Portfolio:0.2% ($4.2M/$1.8B)

Instrument	Shares		Other Manager	Value	% of Portfolio
Taysha Gene Therapies, Inc.(TSHAcusip877619106)	6.5M	QoQ -1.32% (-87.7K) YoY-	All Managers (Combined)	$9.1M	0.5% ($9.1M/$1.8B)	QoQ -20.72% (-$2.4M) YoY-
Cullinan Therapeutics, Inc.(CGEMcusip230031106)	1.2M	QoQ -1.48% (-17.9K) YoY-	All Managers (Combined)	$9.0M	0.5% ($9.0M/$1.8B)	QoQ -38.76% (-$5.7M) YoY-
CrowdStrike Holdings, Inc.(CRWDcusip22788C105)	25.0K	QoQ +4.16% (+1.0K) YoY-	All Managers (Combined)	$8.8M	0.5% ($8.8M/$1.8B)	QoQ +7.33% (+$602.7K) YoY-
Silence Therapeutics plc(SLNcusip82686Q101)	2.8M	QoQ -1.48% (-41.9K) YoY-	All Managers (Combined)	$7.9M	0.4% ($7.9M/$1.8B)	QoQ -59.61% (-$11.6M) YoY-
Alphabet Inc.(GOOGLcusip02079K305)	50.7K	QoQ +624.32% (+43.7K) YoY-	All Managers (Combined)	$7.8M	0.4% ($7.8M/$1.8B)	QoQ +491.70% (+$6.5M) YoY-
Cartesian Therapeutics, Inc.(RNACcusip816212302)	563.3K	QoQ -1.56% (-9.0K) YoY-	All Managers (Combined)	$7.4M	0.4% ($7.4M/$1.8B)	QoQ -27.56% (-$2.8M) YoY-
ADOBE INC.(ADBEcusip00724F101)	19.3K	QoQ +119.34% (+10.5K) YoY-	All Managers (Combined)	$7.4M	0.4% ($7.4M/$1.8B)	QoQ +89.18% (+$3.5M) YoY-
Korro Bio, Inc.(KRROcusip500946108)	418.8K	QoQ 0.00% (-0) YoY-	All Managers (Combined)	$7.3M	0.4% ($7.3M/$1.8B)	QoQ -54.26% (-$8.7M) YoY-
ServiceNow, Inc.(NOWcusip81762P102)	9.1K	QoQ +62.81% (+3.5K) YoY-	All Managers (Combined)	$7.3M	0.4% ($7.3M/$1.8B)	QoQ +22.27% (+$1.3M) YoY-
Seer, Inc.(SEERcusip81578P106)	4.0M	QoQ 0.00% (-0) YoY-	All Managers (Combined)	$6.8M	0.4% ($6.8M/$1.8B)	QoQ -26.83% (-$2.5M) YoY-
PDD Holdings Inc.(PDDcusip722304102)	52.9K	QoQ 0.00% (+0) YoY-	All Managers (Combined)	$6.3M	0.4% ($6.3M/$1.8B)	QoQ +22.02% (+$1.1M) YoY-
Spyre Therapeutics, Inc.(SYREcusip00773J202)	368.6K	QoQ -1.44% (-5.4K) YoY-	All Managers (Combined)	$5.9M	0.3% ($5.9M/$1.8B)	QoQ -31.69% (-$2.8M) YoY-
Gossamer Bio, Inc.(GOSScusip38341P102)	5.2M	QoQ 0.00% (+0) YoY-	All Managers (Combined)	$5.7M	0.3% ($5.7M/$1.8B)	QoQ +21.60% (+$1.0M) YoY-
Oric Pharmaceuticals, Inc.(ORICcusip68622P109)	1.0M	QoQ 0.00% (-0) YoY-	All Managers (Combined)	$5.6M	0.3% ($5.6M/$1.8B)	QoQ -30.85% (-$2.5M) YoY-
Upstream Bio, Inc.(UPBcusip91678A107)	788.5K	QoQ -1.44% (-11.6K) YoY-	All Managers (Combined)	$4.8M	0.3% ($4.8M/$1.8B)	QoQ -63.31% (-$8.3M) YoY-
NVIDIA CORP(NVDAcusip67066G104)	44.4K	QoQ -9.19% (-4.5K) YoY-	All Managers (Combined)	$4.8M	0.3% ($4.8M/$1.8B)	QoQ -26.71% (-$1.8M) YoY-
TAIWAN SEMICONDUCTOR MANUFACTURING CO LTD(TSMcusip874039100)	28.5K	QoQ +90.00% (+13.5K) YoY-	All Managers (Combined)	$4.7M	0.3% ($4.7M/$1.8B)	QoQ +59.70% (+$1.8M) YoY-
Datadog, Inc.(DDOGcusip23804L103)	47.4K	QoQ +55.87% (+17.0K) YoY-	All Managers (Combined)	$4.7M	0.3% ($4.7M/$1.8B)	QoQ +8.22% (+$357.6K) YoY-
Neumora Therapeutics, Inc.(NMRAcusip640979100)	4.4M	QoQ -0.86% (-37.8K) YoY-	All Managers (Combined)	$4.4M	0.2% ($4.4M/$1.8B)	QoQ -90.64% (-$42.2M) YoY-
JFrog Ltd(FROGcusipM6191J100)	131.6K	QoQ +9.57% (+11.5K) YoY-	All Managers (Combined)	$4.2M	0.2% ($4.2M/$1.8B)	QoQ +19.22% (+$679.1K) YoY-